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Frontotemporal Lobar Degeneration clinical trials at UCSF
2 in progress, 1 open to new patients

  • Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL)

    open to eligible people ages 18–85

    Frontotemporal Lobar Degeneration (FTLD) is the neuropathological term for a collection of rare neurodegenerative diseases that correspond to four main overlapping clinical syndromes: frontotemporal dementia (FTD), primary progressive aphasia (PPA), corticobasal degeneration syndrome (CBS) and progressive supranuclear palsy syndrome (PSPS). The goal of this study is to build a FTLD clinical research consortium to support the development of FTLD therapies for new clinical trials. The consortium, referred to as Advancing Research and Treatment for Frontotemporal Lobar Degeneration (ARTFL), will be headquartered at UCSF and will partner with six patient advocacy groups to manage the consortium. Participants will be evaluated at 14 clinical sites throughout North America and a genetics core will genotype all individuals for FTLD associated genes.

    San Francisco, California and other locations

  • Care Ecosystem: Navigating Patients and Families Through Stages of Care

    Sorry, in progress, not accepting new patients

    This is a 3 year clinical trial evaluating the benefits of a program that supports model care for patients with dementia and their family caregivers. Subjects will be recruited from several sites in San Francisco. Subjects determined to be eligible will be consented and randomized into one of two groups. Two thirds of patients will be enrolled into Navigated Care that provides them with assistance in meeting important benchmarks in their care, for example completion of legal and financial planning and strategies for minimizing caregiver burden. One third of patients will be enrolled to a control group, entitled Survey of Care. Outcomes include quality of life, health care utilization, caregiver burden, and satisfaction with care.

    San Francisco, California and other locations