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Meningioma clinical trials at UCSF
3 in progress, 2 open to new patients

  • Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors

    open to eligible people ages up to 18 years

    The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.

    Oakland, California and other locations

  • Vismodegib and FAK Inhibitor GSK2256098 in Treating Patients With Progressive Meningiomas

    open to eligible people ages 18 years and up

    This phase II trial studies how well vismodegib and focal adhesion kinase (FAK) inhibitor GSK2256098 work in treating patients with meningioma that is growing, spreading, or getting worse. Vismodegib and FAK inhibitor GSK2256098 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

    San Francisco, California and other locations

  • Observation or Radiation Therapy in Treating Patients With Grade I, Grade II, or Grade III Meningioma

    Sorry, in progress, not accepting new patients

    RATIONALE: Sometimes a tumor may not need treatment until it progresses. In this case, observation may be sufficient. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor, such as 3-dimensional conformal radiation therapy and intensity-modulated radiation therapy, may kill more tumor cells and cause less damage to normal tissue. It is not yet known whether observation is more effective than radiation therapy in treating patients with meningioma.

    PURPOSE: This phase II trial is studying observation to see how well it works compared with radiation therapy in treating patients with grade I, grade II, or grade III meningioma.

    San Francisco, California and other locations