Skip to main content
Eligibility
for people ages 18 years and up
Location
at San Francisco, California
Dates
study started
Principal Investigator

Description

Summary

The overall goal of this study is to determine if non-invasive imaging with state of the art CT coronary angiography can be used to screen for coronary artery disease in high risk patients prior to liver and lung transplantation. The current protocol for coronary artery disease assessment at UCSF before liver and lung transplantation involves screening with stress tests and/or coronary angiograms in patients with increased risk of coronary artery disease. Coronary angiogram will be used as gold standard for assessment of coronary CTA accuracy.

Official Title

Comparison of Coronary CT Angiography With Conventional Coronary Angiography in Liver and Lung Transplant Candidates.

Keywords

Coronary Artery Disease invasive coronary angiography multidetector coronary CTA detecting coronary artery disease

Eligibility

You can join if…

Open to people ages 18 years and up

  1. Liver transplant candidates referred for invasive coronary angiography which include:

    • Patients with suspicious symptoms for CAD or;
    • Asymptomatic patients;
    • Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo.
  2. Lung transplant candidates referred for invasive coronary angiography which include:

    • Patients with suspicious symptoms for CAD or;
    • Asymptomatic patients;
    • Abnormal non-invasive testing or 1 major risk factor for coronary artery disease or LVEF < 60% on echo in patients with low SVR (typical for ESLD).
  3. Any ethnic background is acceptable.

You CAN'T join if...

  1. Patients with contraindications for the use of iodinated contrast (allergic reaction,renal failure, multiple myeloma, etc) will be excluded.
  2. Children and pregnant women will be excluded because of risks associated with radiation exposure.
  3. Patients must have no atrial fibrillation, as this will interfere with cardiac gating for the examination.
  4. Patients unable to give informed consent will be excluded as well.

Location

Details

Status
currently not accepting new patients, but might later
Start Date
Sponsor
University of California, San Francisco
ID
NCT00727051
Lead Scientist
Karen Ordovas
Study Type
Observational
Last Updated
August 2014
I'm interested in this study!