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Summary

for people ages 18 years and up
at San Francisco, California
study started

Description

Summary

This study will be conducted to determine the pharmacodynamics, cardiovascular and biochemical effects of succinylcholine when given during electroconvulsive therapy. (ECT). This is a single center, prospective, study in patients who will be receiving ECT as indicated and prescribed by their psychiatrist. The study will be performed twice on each patient, 48-72 hours apart during consecutively scheduled ECT procedures.

Official Title

The Muscle Biochemical, Serum Potassium and Cardiovascular Changes After Succinylcholine in Patients Undergoing Electroconvulsive Therapy.

Details

Patients will receive the anesthetic that is traditionally given which includes appropriate doses of succinylcholine. Serum potassium and creatinine phosphokinase (CK) levels will be determined pre and post anesthesia; serum and urine myoglobin will be determined post anesthesia. Vital signs data [i.e., heart rate (arrhythmias) and arterial blood pressure] will be compared pre and post anesthesia. In addition patients will be asked about the presence of muscle pain (myalgia) 1 hour before discharge from the recovery room and the following day post ECT.

Keywords

Depression Succinylcholine

Eligibility

You can join if…

Open to people ages 18 years and up

  1. A male or non-pregnant female aged 18 years and older
  2. American Society of Anesthesiologists physical status 1, 2, 3
  3. Scheduled to undergo electroconvulsive therapy under general anesthesia
  4. Have given written informed consent

You CAN'T join if...

  1. Pregnant or nursing
  2. Any patient in the study investigators opinion who may not be suitable for research.

Location

Details

Status
currently not accepting new patients, but might later
Start Date
Sponsor
University of California, San Francisco
ID
NCT00750906
Study Type
Observational
Last Updated
March 2013