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Eligibility
for people ages up to 30 years
Location
at Oakland, California and other locations
Dates
study started
Principal Investigator

Description

Summary

This study is collecting and storing malignant, borderline malignant neoplasms, and related biological samples from young patients with cancer. Collecting and storing samples of tumor tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help the study of cancer in the future.

Official Title

A Children's Oncology Group Protocol for Collecting and Banking Pediatric Research Specimens Including Rare Pediatric Tumors

Details

OBJECTIVES:

I. Collect malignant, borderline malignant neoplasms, and related biological specimens from Children's Oncology Group institutions for cases in which there is no disease-specific biologic protocol.

II. Provide a repository for long-term storage of malignant, borderline malignant neoplasms, and related biological specimens from these patients.

III. Make specimens available to qualified researchers to understand the biology of cancer in these patients.

OUTLINE:

Tumor tissue samples, blood, and bone marrow aspirates are collected and stored for future analysis.

Keywords

Acute Undifferentiated Leukemia Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative Childhood Acute Lymphoblastic Leukemia Childhood Acute Myeloid Leukemia/Other Myeloid Malignancies Childhood Chronic Myelogenous Leukemia Chronic Lymphocytic Leukemia Hairy Cell Leukemia Juvenile Myelomonocytic Leukemia Mast Cell Leukemia Neoplasm of Uncertain Malignant Potential Prolymphocytic Leukemia Secondary Acute Myeloid Leukemia T-cell Large Granular Lymphocyte Leukemia Unspecified Childhood Solid Tumor, Protocol Specific

Eligibility

For people ages up to 30 years

Inclusion Criteria:

  • Meets any of the following criteria:
  • Diagnosed with primary neoplasm
  • Developed a second malignant neoplasm
  • Any diagnoses having an ICD-O Morphology Code ending in 1, 2, or 3 as listed in the International Classification of Disease for Oncology, Third Edition
  • Must have biological specimens including solid tumors and leukemias available
  • Solid tumors meeting the following criteria:
  • Snap frozen primary tumor OR OCT embedded primary tumor OR formalin fixed(block or tissue in formalin) primary tumor AND at least 10 unstained paraffin slides for NIH Mandated QC (tumors that have undergone central pathology review are allowed)
  • Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
  • Pleural fluid or cytologic specimens meeting the following criteria:
  • At least 1 mL of fluid and at least 2 unstained cytospin slides (or 2 unstained smears)
  • Slides for pathology review (instead of slides for QC) are required for patients with rare tumors
  • ALL/AML
  • 3-6 mL of bone marrow aspirate and 10 mL of whole blood
  • Not eligible for disease-specific biology or banking protocol

Locations

  • Kaiser Permanente-Oakland accepting new patients
    Oakland, California, 94611, USA
  • Lucile Packard Children's Hospital Stanford University accepting new patients
    Palo Alto, California, 94304, USA
  • Southern California Permanente Medical Group accepting new patients
    Downey, California, 90242, USA
  • City of Hope Medical Center accepting new patients
    Duarte, California, 91010, USA
  • Loma Linda University Medical Center accepting new patients
    Loma Linda, California, 92354, USA
  • Miller Children's Hospital accepting new patients
    Long Beach, California, 90806, USA
  • Children's Hospital Los Angeles accepting new patients
    Los Angeles, California, 90027, USA
  • Cedars-Sinai Medical Center accepting new patients
    Los Angeles, California, 90048, USA
  • David Geffen School of Medicine at UCLA accepting new patients
    Los Angeles, California, 90095, USA
  • Mattel Children's Hospital UCLA accepting new patients
    Los Angeles, California, 90095, USA
  • Children's Hospital Central California accepting new patients
    Madera, California, 93636, USA
  • Childrens Hospital of Orange County accepting new patients
    Orange, California, 92868, USA
  • Rady Children's Hospital - San Diego accepting new patients
    San Diego, California, 92123, USA

Details

Status
accepting new patients
Start Date
Sponsor
Children's Oncology Group
ID
NCT00898079
Lead Scientist
Robert Goldsby
Study Type
Observational
Last Updated
November 2016
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