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Summary

for people ages 1–99 (full criteria)
healthy people welcome
at San Francisco, California and other locations
study started

Description

Summary

The human Prion diseases can be classified into sporadic, acquired and inherited forms. Inherited forms usually manifest in higher age so there have to be factors preventing Prion propagation in young mutation carriers. Antibodies against the flexible tail of Prions have been shown to be protective in mice. The investigators intend to screen mutation carriers and controls for the presence of Prion autoantibodies.

Keywords

Prion Diseases Antibodies

Eligibility

You can join if…

Open to people ages 1–99

  • Relatives of patients of genetic Prion diseases
  • Obtained informed consent

You CAN'T join if...

  • No informed consent

Locations

  • University Medical Center Göttingen accepting new patients
    Göttingen, Germany
  • Institute of Neuropathology accepting new patients
    Zürich, Switzerland
  • Medical University Graz accepting new patients
    Graz, Austria
  • Slovak Medical University accepting new patients
    Bratislava, Slovakia
  • Istituto di Ricerche Farmacologiche accepting new patients
    Milano, Italy
  • CJD Foundation Israel accepting new patients
    Pardes Hanna, Israel

Details

Status
accepting new patients
Start Date
Sponsor
University of Zurich
ID
NCT02837705
Study Type
Observational [Patient Registry]
Last Updated
July 2016
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