This study is conducted to better understand Post-Traumatic Stress Symptoms (PTSS) in adolescent transplant recipients and their parent/guardian and to see if PTSS play a role in the way adolescent transplant recipients take their prescribed medicine. Target population: medically stable adolescent solid organ (e.g., heart, kidney, liver, lung, small bowel) transplant recipients and their parent(s)/guardian.
Prevalence and Correlates of Post-Traumatic Stress Symptoms (PTSS) in Adolescent Solid Organ Transplant Recipients (CTOTC-11)
Solid Organ Transplant RecipientsParent(s)/Guardian of Referenced Transplant RecipientsTransplant recipientsAdolescentsPost-Traumatic Stress Symptoms (PTSS)Transplant Recipient and Family Impact(s)
You can join if…
Open to people ages 12 years to 17 years
and/or their parent(s)/guardian must be able to understand and provide informed consent in English or Spanish;
is prescribed tacrolimus (either brand or generic formulation); and
has been seen in the enrolling center's clinic at least twice in the last two years.
You CAN'T join if...
received a transplant less than 18 months prior to enrollment;
has had more than one transplant (including marrow replacement);
or their parent(s)/guardian is actively psychotic or severely disoriented due to any cause, including hepatic encephalopathy (temporary exclusion);
or their parent(s)/guardian has been diagnosed with severe intellectual disability as defined in the Diagnostic and Statistical Manual of Mental Disorders, 5th edition(DSM-5);
is not medically stable or is hospitalized;
is currently enrolled in a study that aims to improve adherence to medical recommendations;
is receiving cognitive behavioral therapy for confirmed or suspected diagnosis of Post-Traumatic Stress Disorder (PTSD) at enrollment;
is receiving psychotropic medications for a confirmed or suspected diagnosis of PTSD.
UCSF Benioff Children's Hospital: Pediatric Transplantationaccepting new patients San Francisco, California, 94143, USA
Lucile Salter Packard Children's Hospital at Stanford: Pediatric Transplantationnot yet accepting patients Palo Alto, California, 94304, USA
Ronald Reagan UCLA Medical Center: Pediatric Transplantationnot yet accepting patients Los Angeles, California, 90095, USA
accepting new patients
National Institute of Allergy and Infectious Diseases (NIAID)