Anticoagulation clinical trials at UCSF
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The overarching goal of this project is to assess the impact and cost-effectiveness of system-level and patient-facing interventions on anticoagulation treatment and characterize the current state of safety for Direct Oral Anticoagulants (DOACs). The investigators focus on examining implementation factors and cost-effectiveness, which are critical to helping health care decision-makers prioritize finite resources, particularly in safety-net health systems where a disproportionate number of Agency for Healthcare Research and Quality's Priority Populations—low-income and racial/ ethnic minority groups—receive care. Therefore, the investigators propose to implement an Health Information Technology (HIT) population management tool with patient-facing outreach and team-based workflow, the AntiCoagulation Tracking InterVention and Evaluation (ACTIVE), and examine its effect on anticoagulation management outcomes in two diverse settings - a safety net hospital and a large academic medical center - hypothesizing that such interventions can be cost-effective strategies to improve patient safety.