Blood Platelets clinical trials at UCSF
1 research study open to eligible people
Blood platelets are important because they help your blood to clot. There is a clinical trial now recruiting at UCSF for people who have had an injury that caused bleeding. The trial will study how changes in platelets after an injury can affect outcomes and potentially lead to better treatments.
Post-Injury Platelet Biology: Mechanisms and Outcomes
open to eligible people ages 18 years and up
Trauma-induced coagulopathy is a central cause of preventable deaths from hemorrhage after injury. The contribution and impact of altered post injury platelet biology on trauma-induced coagulopathy is not well understood despite the pivotal contribution of platelets to normal coagulation and endothelial integrity. The central hypothesis for this study is that severe injury and shock drive altered platelet activation, platelet aggregation, and platelet-endothelial interactions that are associated with increased rates of transfusion, organ failure, and mortality. This study will investigate these causal pathways, mechanisms, and associated outcomes in a prospective observational trauma cohort through collection of biospecimens and detailed clinical data.
San Francisco, California
Our lead scientists for Blood Platelets research studies include Lucy Kornblith, MD.
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