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Childhood Mortality clinical trials at UCSF
3 in progress, 0 open to new patients

  • Mortality Reduction After Oral Azithromycin Contingency: Mortality Study

    Sorry, not currently recruiting here

    In the event that MORDOR (NCT02047981) established the efficacy of oral azithromycin in preventing mortality in 1-59 month children, the contingency study was to treat both arms in Niger with oral azithromycin (unmasked) for two more years in Niger only.

    San Francisco, California and other locations

  • Mortality Reduction After Oral Azithromycin: Morbidity Study

    Sorry, not currently recruiting here

    The long-term goal of this study is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood morbidity and increasing growth, and for the potential selection of antibiotic resistance. The investigators propose a set of 3 cluster-randomized trials comparing communities randomized to oral azithromycin with those randomized to placebo. To assess the generalizability of the intervention, investigators will monitor for antibiotic resistance, which could potentially limit adoption of mass antibiotic treatments. The investigators will also assess several measures of infectious diseases. The investigators hypothesize that mass azithromycin treatments will reduce childhood morbidity and will be accompanied by an acceptable level of antibiotic resistance.

    San Francisco, California and other locations

  • Mortality Reduction After Oral Azithromycin: Mortality Study

    Sorry, not currently recruiting here

    Our long-term goal is to more precisely define the role of mass azithromycin treatments as an intervention for reducing childhood mortality. We propose a single multi-site (multi-country), cluster-randomized trial comparing communities randomized to oral azithromycin with those randomized to placebo. We hypothesize that mass azithromycin treatments will reduce childhood mortality.

    San Francisco, California and other locations