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IDH2 Mutation clinical trials at UCSF
1 in progress, 0 open to eligible people

  • BGB-290 and Temozolomide in Treating Patients With Recurrent Gliomas With IDH1/2 Mutations

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    This phase I/II trial studies the side effects and how well BGB-290 and temozolomide work in treating patients with gliomas (brain tumors) with IDH1/2 mutations that have come back. BGB-290 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving BGB-290 and temozolomide may work better in treating patients with recurrent gliomas.

    San Francisco, California and other locations

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