Summary

for people ages 50 years and up (full criteria)
at San Francisco, California
study started
estimated completion:
Marlene Grenon

Description

Summary

The hypothesis being tested is that in patients with stable claudication and documented PAD, omega-3 supplementation for 1 month will lead to improvement in endothelial function as measured by flow-mediated, brachial artery vasodilation (FMD), as well as improvement in the vascular inflammatory profile as measured by a panel of established circulating inflammatory biomarkers.

Keywords

Peripheral Arterial Disease Inflammation Peripheral Vascular Diseases Pro-Omega Omega 3 Fatty Acid

Eligibility

You can join if…

Open to people ages 50 years and up

  • intermittent claudication
  • resting or exercise Ankle-Brachial Index (ABI) <0.9
  • age 50 and more

You CAN'T join if...

  • critical limb ischemia
  • hypersensitivity/allergies to fish or seafood
  • already on omega-3 fatty acids or equivalent
  • significant renal, hepatic, and inflammatory disease
  • concurrent severe infections
  • acute illness (MI, stroke, major surgery within 30 days)
  • receiving immunosuppressive medications or steroids

Location

  • University of California San Francisco accepting new patients
    San Francisco California 94115 United States

Details

Status
accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of California, San Francisco
ID
NCT01310270
Phase
Phase 2
Lead Scientist
Marlene Grenon
Study Type
Interventional
Last Updated
January 2, 2018