for people ages 12-24 (full criteria)
at San Francisco, California and other locations
study started
estimated completion
Andrea Garber



The purpose of this study is to compare the efficacy, safety, and cost-effectiveness of lower calorie refeeding versus higher calorie refeeding in hospitalized adolescents with anorexia nervosa.

Official Title

Multi-center Randomized Controlled Trial of Refeeding in Anorexia Nervosa


Anorexia Nervosa eating disorders refeeding adolescent medicine nutritional rehabilitation Anorexia Higher Calorie Refeeding Lower Calorie Refeeding Higher Calorie Refeeding Protocol Lower Calorie Refeeding Protocol


You can join if…

Open to people ages 12-24

  • diagnosis of AN
  • atypical AN
  • no hospital admissions for the previous six months
  • meet hospitalization criteria: daytime heart rate (HR) < 50 bpm or night time HR < 45 bpm, blood pressure (BP) <90/45 mmHg, temperature < 35.6° C, or symptomatic orthostasis defined by increase in HR > 35 bpm or decrease in systolic BP > 20 mmHg or decrease in diastolic BP > 10 mmHg from lying to standing

You CAN'T join if...

  • diagnosis of bulimia nervosa [DSM-5]
  • currently in remission (as defined by weight and EDE-Q score)
  • admission for food refusal without malnutrition
  • current pregnancy
  • chronic disease (e.g. immune/endocrine disorders, pulmonary, cardiac, or renal disease)
  • current suicidality or psychosis
  • < 60% mBMI


  • University of California, San Francisco Benioff Children's Hospital
    San Francisco California 94158 United States
  • Stanford University Lucille Packard Children's Hospital
    Palo Alto California 94304 United States

Lead Scientist

  • Andrea Garber
    Dr. Garber is an Associate Professor of Pediatrics in the Division of Adolescent Medicine at the University of California, San Francisco (UCSF), with a joint appointment in the School of Public Health at the University of California, Berkeley (UCB). She is a nutritionist, with a PhD in Human and Clinical Nutrition from the University of Wisconsin-Madison, and a Registered Dietitian (RD) from UCSF.


in progress, not accepting new patients
Start Date
Completion Date
University of California, San Francisco
Study Type
Last Updated