Summary

for people ages 1-99 (full criteria)
healthy people welcome
at San Francisco, California and other locations
study started
estimated completion

Description

Summary

The human Prion diseases can be classified into sporadic, acquired and inherited forms. Inherited forms usually manifest in higher age so there have to be factors preventing Prion propagation in young mutation carriers. Antibodies against the flexible tail of Prions have been shown to be protective in mice. The investigators intend to screen mutation carriers and controls for the presence of Prion autoantibodies.

Keywords

Prion DiseasesAntibodiesblood drawcarriers of a mutation in the Prion genefamily members of carriers of a mutation in the Prion gene

Eligibility

You can join if…

Open to people ages 1-99

  • Relatives of patients of genetic Prion diseases
  • Obtained informed consent

You CAN'T join if...

  • No informed consent

Locations

  • UCSF Memory and Aging Center
    San FranciscoCaliforniaUnited States
  • University Medical Center Göttingen
    GöttingenGermany

Details

Status
in progress, not accepting new patients
Start Date
Completion Date
(estimated)
Sponsor
University of Zurich
ID
NCT02837705
Study Type
Observational [Patient Registry]
Last Updated