for people ages 18 years and up (full criteria)
at San Francisco, California and other locations
study started
estimated completion:



This study is designed to assess the usefulness of 18F-AV-1451 in Positron Emission Tomography imaging for subjects diagnosed with Frontotemporal Dementia.

Official Title

18F-AV-1451 PET Imaging in Subjects With Frontotemporal Dementia


Frontotemporal Dementia Dementia Aphasia, Primary Progressive Pick Disease of the Brain 18F-AV-1451 18F-AV-45


You can join if…

Open to people ages 18 years and up

  • Have provided informed consent or have a legally authorized (LAR) provide consent for study procedures
  • Have had volumetric brain MRI obtained in site's companion protocol within one year of enrollment
  • Can tolerate PET scan procedures

You CAN'T join if...

  • Have clinically significant cardiac, hepatic, renal, pulmonary, metabolic, or endocrine disturbances that pose potential safety risk
  • Have history of risk factors for Torsades de Pointes (TdP) or taking medication known to cause QT prolongation
  • Have history of drug or alcohol dependence within the last year
  • Are females of childbearing potential who are not surgically sterile, not refraining from sexual activity, or not using reliable contraception
  • Have history of relevant severe drug allergy or hypersensitivity
  • Have received an investigational medication under FDA IND protocol within 30 days of planned imaging session
  • Have received a radiopharmaceutical for imaging/therapy within 24 hours of imaging session
  • Possess PET scan evidence of amyloid deposition
  • Determined by the investigator to be unsuitable for this type of study


  • Memory and Aging Center, UCSF accepting new patients
    San Francisco California 94158 United States
  • Movement Disorder Center, UCSD accepting new patients
    La Jolla California 92037 United States


accepting new patients
Start Date
Completion Date
Avid Radiopharmaceuticals
Phase 1
Study Type
Last Updated