Summary

for people ages 18 years and up (full criteria)
at San Francisco, California and other locations
study started
Jeffrey Ralph

Description

Summary

The purpose of this program is to provide expanded access to Inotersen for up to 100 Patients with Hereditary Transthyretin Amyloidosis (hTTR).

Official Title

Expanded Access Program for Inotersen (ISIS 420915) in Patients With Hereditary Transthyretin Amyloidosis (hATTR)

Details

The Program is intended to provided expanded access to Inotersen for eligible patients with hATTR who have limited or no available treatment options.

Keywords

Amyloidosis, Hereditary Amyloidosis Amyloidosis, Familial Inotersen

Eligibility

You can join if…

Open to people ages 18 years and up

  • Male or female at least 18 years of age with a diagnosis of hATTR
  • Symptoms consistent with polyneuropathy
  • Meet Polyneuropathy Disability (PND) Stage I-III requirements

You CAN'T join if...

  • Known Primary Amyloidosis, Leptomeningeal Amyloidosis or Monoclonal Gammopathy of Undetermined Significance or Multiple Myeloma
  • Have inadequate cardiac function
  • Have low platelet counts
  • Have inadequate renal function

Locations

  • University of California - San Francisco
    San Francisco California 94143 United States
  • Stanford University
    Palo Alto California 94305 United States

Details

Status
not accepting new patients
Start Date
Sponsor
Ionis Pharmaceuticals, Inc.
ID
NCT03400098
Lead Scientist
Jeffrey Ralph
Study Type
Expanded Access
Last Updated
July 13, 2018