for people ages 18 years and up (full criteria)
study started
estimated completion



Purpose: The overall objective of this study is to assess whether the Transitions Clinic Network (TCN) program, which provides enhanced primary care and opioid use disorder (OUD) treatment for people recently released from incarceration, improves measures in the opioid treatment cascade compared to referral to standard primary care. Participants: 800 individuals currently receiving medications for OUD released from six local jails (Bridgeport, CT; Bronx, NY; Caguas, PR; Durham, NC; Minneapolis, MN; Rochester, NY) Procedures (methods): This is a hybrid type I effectiveness-implementation trial will randomize 800 people to one of two treatment conditions: TNC and referral to opioid treatment program (OTP) or standard care and referral to OTP. People will complete the recruitment process while in jail (screening, consent, baseline assessments, and randomization). Post incarceration participants will meet with research assistants for a structured interview and urine toxicology screening at 1, 6, and 12 months, and a phone interview at months 3 and 9. 120 people will be selected to participate in Ecological Momentary Assessment (EMA) to access both the acceptability and appropriateness of the TCN intervention and the multi-level facilitators and barriers of OUD treatment engagement in the first 30 days following release from incarceration.


Opioid Addiction Opioid-Related Disorders Behavior, Addictive Transitions Clinic Network Primary Care


You can join if…

Open to people ages 18 years and up

  • 18 years or older
  • English and Spanish-speaking,
  • Meeting current DSM-5 criteria for OUD, and are on MOUD prior to release from jail.

You CAN'T join if...

  • acutely psychotic, suicidal or homicidal,
  • require prescription opioids for acute pain, chronic pain or palliative care without OUD,
  • have a planned relocation that makes it unlikely they would be able to complete the study and follow-up assessments,
  • have a primary care provider that they already have established care with in the community,
  • women of child-bearing age will be excluded if they are pregnant


not yet accepting patients
Start Date
Completion Date
Yale University
Study Type
Last Updated