for people ages 18-80 (full criteria)
at San Francisco, California
study started
estimated completion
Principal Investigator
by Arthur Wallace, MD, PhD
Photo of Arthur Wallace
Arthur Wallace



Collect continuous systolic and diastolic blood pressure values and waveforms as recorded by an arterial line catheter and by non-invasive blood pressure (NIBP) and to collect Photoplethysmogram Pulse Oximetry (PPG) waveform in order to optimize the Sensifree algorithm.

Official Title

Evaluation of Sensifree's Algorithm for Continuous Blood Pressure Measurements Based on a PPG Sensor's Signal Compared to Invasive Radial Arterial Line


Sensifree is developing a continuous non-invasive blood pressure measurement system, that uses a fingertip PPG sensor as a signal source. The system provides systolic, diastolic and mean arterial pressure values, for use in hospitals and other clinical settings. The PPG waveform is analyzed by a proprietary software algorithm, calculating BP values. The current best method to obtain similar information is by using an Arterial line catheter which will serve as a reference device. In this study, the sponsor aims to prospectively collect continuous radial arterial line & PPG waveforms, as well as NIBP data over the period of the surgery in order to test and refine the algorithm.


Blood Pressure Measurement Arterial catheterization kit GE Datex-Ohmeda Finger Clip Pulse Oximeter Sensor NIBP Cuff (GE Healthcare)


You can join if…

Open to people ages 18-80

  1. Signed inform consent
  2. Age 18 or greater
  3. Elective surgery that requires invasive BP monitoring (A-line)

You CAN'T join if...

  1. Emergency surgery
  2. A-line not inserted
  3. Informed consent not signed


  • San Francisco Veterans Affairs Medical Center accepting new patients
    San Francisco California 94121 United States

Lead Scientist at UCSF

  • Arthur Wallace, MD, PhD
    Art Wallace, M.D., Ph.D. is a professor and vice-chair of anesthesiology and perioperative care at the University of California, San Francisco and Chief of the Anesthesia Service at the Veterans Affairs Medical Center in San Francisco. His clinical practice includes cardiac and non-cardiac anesthesiology as well as ICU and preoperative clinical care. He completed a B.S.


accepting new patients
Start Date
Completion Date
Sensifree Ltd.
Study Type
Last Updated