Wound and Injuries clinical trials at UCSF
1 research study open to eligible people
Wounds and injuries can cause serious bleeding that can lead to death. UCSF is running a clinical trial to learn about how platelets after an injury can help reduce this type of bleeding. They want to find out how changing these platelets can make people safer after they are hurt. If you are interested, you can join the study.
open to eligible people ages 18 years and up
Trauma-induced coagulopathy is a central cause of preventable deaths from hemorrhage after injury. The contribution and impact of altered post injury platelet biology on trauma-induced coagulopathy is not well understood despite the pivotal contribution of platelets to normal coagulation and endothelial integrity. The central hypothesis for this study is that severe injury and shock drive altered platelet activation, platelet aggregation, and platelet-endothelial interactions that are associated with increased rates of transfusion, organ failure, and mortality. This study will investigate these causal pathways, mechanisms, and associated outcomes in a prospective observational trauma cohort through collection of biospecimens and detailed clinical data.
San Francisco, California
Our lead scientists for Wound and Injuries research studies include Lucy Kornblith, MD.