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Epilepsy clinical trials at UCSF
4 in progress, 2 open to new patients

  • Stereotactic Laser Ablation for Temporal Lobe Epilepsy

    open to eligible people ages 18 years and up

    The study is designed to evaluate the safety and efficacy of the Visualase MRI-guided laser ablation system for mesial temporal epilepsy (MTLE).

    San Francisco, California and other locations

  • The Human Epilepsy Project

    open to eligible people ages 12–60

    HEP is a five-year, prospective, observational study whose primary goal is to identify clinical characteristics and biomarkers predictive of disease outcome, progression, and treatment response in participants with newly treated focal epilepsy.

    San Fancisco, California and other locations

  • RNS® System Epilepsy PAS

    Sorry, accepting new patients by invitation only

    The purpose of the study is to follow patients with partial onset seizures prospectively over 5 years in the real-world environment to gather data on the long-term safety and effectiveness of the RNS System at qualified CECs by qualified neurologists, epileptologists, and neurosurgeons trained on the RNS System.

    San Francisco, California and other locations

  • SANTE - Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy

    Sorry, in progress, not accepting new patients

    The purpose of this research is to study the safety and effectiveness of bilateral stimulation of the anterior nucleus of the thalamus as adjunctive therapy for reducing the frequency of seizures in adults diagnosed with epilepsy characterized by partial-onset seizures, with or without secondary generalization, that are refractory to antiepileptic medications.