Clinical Trials Open to Healthy Volunteers

• 4-Repeat Tauopathy Neuroimaging Initiative - Cycle 2

  • study on Corticobasal Degeneration and Corticobasal Syndrome
  • open to healthy people ages 40-80

• A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

  • study on Postoperative Delirium and Postoperative Pain
  • open to healthy people ages 60 years and up

• A Couples-based Intervention for Transgender Women and Their Partners

  • study on HIV/AIDS
  • open to healthy people ages 18 years and up

• A Distress Reduction Intervention for Patients With BCR-ABL-Negative MPNs or CML on Tyrosine Kinase Inhibitors

  • study on Myeloproliferative Neoplasms and Leukemia
  • open to healthy people ages 18 years and up

• A Neuroimaging Study of Open-label Placebo in Depressed Adolescents

  • study on Depression
  • open to healthy people ages 13-18

• A Silver Lining in the VAD Sky

  • study on Driveline Infections
  • open to healthy people ages 18 years and up

• Acoustic Enhancer Research on Laser Lithotripsy (AEROLITH)

  • study on Urinary Stones
  • open to healthy people ages 18-75

• Addressing Heavy Alcohol Use Consumption With Kudzu

  • study on Alcohol Use and Sexually Transmitted Infections
  • open to healthy people ages 18-70

• AI Activity Study in Patients With Elevated Blood Pressure

  • study on High Blood Pressure
  • open to healthy people ages 18 years and up

• Alzheimer's Disease Neuroimaging Initiative 3 (ADNI3) Protocol

  • study on Mild Cognitive Impairment and Alzheimer's Disease
  • open to healthy people ages 55-90

• American Lung Association (ALA) Lung Health Cohort

  • study on Lung Diseases
  • open to healthy people ages 25-35

• An Adaptive Intervention for Depression Among Latinos Living With HIV.

  • study on Depression and HIV/AIDS
  • open to healthy people ages 18 years and up

• ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

  • study on Frontotemporal Lobar Degeneration and Progressive Supranuclear Palsy
  • open to healthy people ages 18 years and up

• Artificial Urinary Sphincter Clinical Outcomes

  • study on Urinary Incontinence
  • open to healthy males ages 18 years and up

• Assessing the Safety of Pregnancy In the CoRonavirus (COVID-19) pandEmic

  • study on COVID-19 and Pregnancy
  • open to healthy females ages 18 years and up

• Assessment and Prevention of Pain During Ovarian Stimulation in Patients With Endometriosis

  • study on Endometriosis and Ovarian Hyperstimulation
  • open to healthy females ages 18-42

• Attachment and Biobehavioral Catch-up and Depression Treatment

  • study on Depression and Child Behavior Problem
  • open to healthy females ages 18 years and up

• Backpack Weight Impacts

  • open to healthy people ages 18-65

• Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research

  • study on Neurodegenerative Disease
  • open to healthy people ages 18 years and up

• Cellular Aging and Neurobiology of Depression Study

  • study on Depression
  • open to healthy people ages 21-60

• CF And Effects of Drugs Mixed Ex Vivo With Sputum for Mucolytic Treatment

  • study on Cystic Fibrosis and Fibrosis
  • open to healthy people ages 18-65

• Characterization of Adult Subjects for Asthmatic Research Studies

  • study on Asthma
  • open to healthy people ages 18 years and up

• Characterizing Asthma Sputum Elasticity in the UCSF Severe Asthma Research Program

  • study on Asthma
  • open to healthy people ages 18-65

• Childhood Cancer Survivor Study

  • study on Cancer, General
  • open to healthy people

• Clinical and Biological Characteristics of Hidradenitis Suppurativa

  • study on Hidradenitis Suppurativa
  • open to healthy people ages 13 years and up

• Collaborative Approach to Examining Adversity and Building Resilience Study

  • study on Early Life Adversity and Caregiver Stress
  • open to healthy people ages 2 years and up

• Collection of Blood for Multiple Collaborative Studies

  • study on HIV/AIDS
  • open to healthy people ages 18 years and up

• Comparative Effectiveness of MRgFUS Versus CTgRFA for Osteoid Osteomas

  • study on Osteoid Osteoma
  • open to healthy people ages 8 years and up

• Comparing Intra-vaginal Culture of Embryos to In-vitro Culture of Embryos With Minimal Stimulation

  • study on Infertility
  • open to healthy females ages 18-37

• Comparing Mobile Health Strategies to Improve Pre-exposure Prophylaxis Use (PrEP) for HIV Prevention

  • study on HIV/AIDS and Sexually Transmitted Infections
  • open to healthy people ages 15 years and up

• CONNECT: Smoking Cessation and Lung Cancer Screening

  • study on Smoking Cessation and Lung Cancer
  • open to healthy people ages 55-80

• Contingency Management for Smoking Cessation

  • study on Smoking Cessation and Tobacco
  • open to healthy people ages 18 years and up

• Continuous Versus Cyclical OCP Use in PCOS

  • study on Polycystic Ovary Syndrome
  • open to healthy females ages 15-40

• Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke

  • study on Smoke Inhalation and Exposure to Pollution
  • open to healthy people ages 18-50

• COVID-19 Variant Immunologic Landscape Trial (COVAIL Trial)

  • study on COVID-19
  • open to healthy people ages 18 years and up

• Dermatologic Research Evaluation and Monitoring of Sleep in Moderate-to-Severe Psoriasis

  • study on Psoriasis
  • open to healthy people ages 18 years and up

• Determining Normal Range for Free Light Chains in Serum Among Twins

  • study on Multiple Myeloma
  • open to healthy people ages 18-80

• Dexamethasone in Total Knee Arthroplasty

  • study on Total Knee Arthroplasty
  • open to healthy people ages 18 years and up

• Dexamethasone Solution and Dexamethasone in Mucolox™

  • study on Oral Lichen Planus and Mucous Membrane Pemphigoid
  • open to healthy people ages 18 years and up

• Diabetes and Depression Text Messaging Intervention

  • study on Diabetes and Depression
  • open to healthy people ages 18-75

• Direct-to-patient Teledermatology and Computer-assisted Diagnosis

  • study on New Patient Use of Teledermatology Mobile App
  • open to healthy people ages 18 years and up

• Dopaminergic Mechanisms Underlying Human Social Behavior

  • study on Decision Making and Executive Function
  • open to healthy people ages 18-40

• Double-Blind Randomized Controlled Trial for the Evaluation of a Novel Adaptive Attention Training in Healthy Adolescents

  • study on Attention Training
  • open to healthy people ages 12-16

• Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery

  • study on Major Abdominal/GI Surgery
  • open to healthy people ages 18 years and up

• Endoscopic Surgery for Bariatric Revision After Weight Loss Failure

  • study on Obesity and Weight Loss
  • open to healthy people ages 18 years and up

• Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study

  • study on Premature Birth and Pregnancy Preterm
  • open to healthy females

• Engaging Sexual and Gender Minority Cigarette Smokers Into Social Media-based Treatment

  • study on Smoking Cessation and Nicotine Dependence
  • open to healthy people ages 18 years and up

• Enhancing Cognitive Control Abilities Using Mobile Technology in a Senior Living Community

  • study on Aging and Cognitive Change
  • open to healthy people ages 50 years and up

• Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

  • study on Huntington's Disease
  • open to healthy people ages 18 years and up

• Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

  • study on Nicotine Administration & Dosage and Electronic Cigarettes
  • open to healthy people ages 21-70

• Evaluating the Feasibility of VR for Pediatric Renal Biopsies

  • study on Pain, Procedural and Procedural Anxiety
  • open to healthy people ages 5-17

• Evaluation of BIS™ and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)

  • study on Anesthesia
  • open to healthy people ages 18-60

• Evaluation of Doxycycline Post-exposure Prophylaxis to Reduce Sexually Transmitted Infections in PrEP Users and HIV-infected Men Who Have Sex With Men

  • study on Gonorrhea and Chlamydia
  • open to healthy males ages 18 years and up

• Evaluation of Patient Outcomes From the Kidney Allograft Outcomes AlloSure Registry

  • study on Kidney Transplant
  • open to healthy people ages 18 years and up

• Examine the Effects of Mindfulness in Woman With a History of Child Adversity

  • study on Stress and Psychological Stress
  • open to healthy females ages 30-50

• EyeConic: Qualification for Cone-Optogenetics

  • study on Retinal Dystrophies
  • open to healthy people

• Family Mental Health Family Navigator Project (FMHN)

  • study on Mental Health
  • open to healthy people ages 12-17

• Getting Asian Americans INFORMED to Facilitate COVID-19 Testing and Vaccination

  • study on Educational Activities and COVID-19
  • open to healthy people ages 18 years and up

• Guselkumab Immunogenetics

  • study on Psoriasis and Guttate Psoriasis
  • open to healthy people ages 18 years and up

• HIV Prevention Peer Navigation for Justice Involved Women

  • study on HIV/AIDS and Stigma, Social
  • open to healthy females ages 18-49

• Hypertension in Young Adults Trial

  • study on High Blood Pressure
  • open to healthy people ages 18-35

• Identification and Validation of Biomarkers for Breast Cancer Resistance Protein (BCRP)

  • study on Breast Cancer
  • open to healthy people ages 18-64

• Identification of Microbial DNA in Maternal Plasma After PPROM

  • study on Preterm Rupture of Membranes
  • open to healthy females ages 18-55

• Impact of Breast Cancer Treatment on Joint Health, Cartilage Composition, and Bone Structure in the Knee and Hand

  • study on Breast Cancer
  • open to healthy people ages up to 70 years

• Impact of Very Low Nicotine Content Cigarettes in a Complex Marketplace

  • study on Smoking Cessation and Tobacco
  • open to healthy people ages 21 years and up

• Implementing an Individualized Pain Plan (IPP) for ED Treatment of VOE's in Sickle Cell Disease

  • study on Sickle Cell Anemia and Genetic Diseases
  • open to healthy people ages 18-45

• Incorporating ePrognosis for the Encouragement of Smarter Screening for Breast and Colorectal Cancer in Older Adults

  • study on Breast Cancer and Colorectal Cancer
  • open to healthy people ages 70 years and up

• Induced Pluripotent Stem Cells for Disease Research

  • study on Hirschsprung Disease
  • open to healthy people ages 13-100

• Inflammation, Diabetes, Ethnicity and Obesity Cohort

  • study on Obesity and Diabetes
  • open to healthy people ages 18-75

• Innate Immunity in Ozone-induced Airway Inflammation in COPD

  • study on Chronic Obstructive Pulmonary Disease and Airway Disease
  • open to healthy people ages 45-75

• Intermittent Oral Naltrexone Enhanced With an Ecological Momentary Intervention for Methamphetamine-using MSM

  • study on Methamphetamines
  • open to healthy males ages 18-70

• KIDney Injury in Times of COVID-19 (KIDCOV)

  • study on COVID-19 and Acute Kidney Injury
  • open to healthy people ages 18 years and up

• Longitudinal Early-onset Alzheimer's Disease Study Protocol

  • study on Alzheimer's Disease and Mild Cognitive Impairment
  • open to healthy people ages 40-64

• Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome

  • study on Sturge-Weber Syndrome
  • open to healthy people

• Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers

  • study on Chronic Obstructive Pulmonary Disease and Smoking Cessation
  • open to healthy people ages 40-75

• Mail Order Mifepristone Study

  • study on Abortion and Pregnancy
  • open to healthy females ages 15 years and up

• Medial-prefrontal Enhancement During Schizophrenia Systems Imaging

  • study on Schizophrenia
  • open to healthy people ages 18-60

• Missed Period Pill Study

  • study on Menstrual Regulation and Menstrual Irregularity
  • open to healthy females ages 18 years and up

• N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use

  • study on Cannabis and Tobacco
  • open to healthy people ages 18 years and up

• N95 Reuse During COVID-19

  • study on Emergency Medicine and Frontline Providers
  • open to healthy people ages 18 years and up

• Near Infrared Spectroscopy (NIRS) for Assessment of Depression

  • study on Depression
  • open to healthy people ages 18 years and up

• Neurofilament Surveillance Project (NSP)

  • study on Dementia and Frontotemporal Dementia
  • open to healthy people ages 18-85

• Novel Quantitative MRI for Axial Spondyloarthritis

  • study on Ankylosing Spondylitis and Spondyloarthritis
  • open to healthy people ages 18 years and up

• Optimizing Acute Post-Operative Dental Pain Management Using New Health Information Technology

  • study on Postoperative Pain and Complication, Postoperative
  • open to healthy people ages 18 years and up

• Parenting Stress mHealth

  • study on Stress
  • open to healthy people ages 12 years and up

• Parkinson Progression Marker Initiative Online (PPMI Online)

  • study on Parkinson's Disease
  • open to healthy people ages 18 years and up

• Patient Portal and Navigation Program in Providing Information for Asian American Cancer Patients

  • study on Caregivers and Malignant Neoplasm
  • open to healthy people ages 21 years and up

• Peripheral Nerve Blocks for Major Lower Extremity Amputations

  • study on Postoperative Pain
  • open to healthy people ages 18 years and up

• PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)

  • study on HIV/AIDS
  • open to healthy people ages 18 years and up

• Physical Activity and Fertility Care Study

  • study on Infertility
  • open to healthy females ages 18-43

• Pilot Study of Pancreatic Cancer Screening

  • study on Pancreatic Cancer
  • open to healthy people ages 18 years and up

• Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

  • study on Hernia
  • open to healthy females ages 18 years and up

• Post-Injury Platelet Biology: Mechanisms and Outcomes

  • study on Wound and Injuries and Blood Platelets
  • open to healthy people ages 18 years and up

• PPMI 2.0 Clinical -Establishing a Deeply Phenotyped PD Cohort

  • study on Parkinson's Disease
  • open to healthy people ages 30 years and up

• Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans

  • study on Pain
  • open to healthy people ages 18 years and up

• PrEP Affect Regulation Treatment Innovation

  • study on Medication Adherence and HIV/AIDS
  • open to healthy males ages 18 years and up

• Prevention of Colorectal Cancer Through Multiomics Blood Testing

  • study on Colon Cancer and Colorectal Cancer
  • open to healthy people ages 45-85

• Progression and Etiology of Cortical Porosity in Diabetic Bone Disease

  • study on Diabetes and Diabetes Type 2
  • open to healthy people ages 50-70

• Prophylactic Reinforcement of Ventral Abdominal Incisions Trial

  • study on Open Midline Laparotomy and Hernia
  • open to healthy people ages 18 years and up

• Reaching for Equity in Sleep Apnea Treatment (REST) Study

  • study on Sleep Apnea and Sleep Disorders
  • open to healthy people ages 18 years and up

• Reducing Pesticide Exposures in Child Care Centers

  • study on Risk Reduction and Environmental Exposure
  • open to healthy people ages 3-75

• Retinal Imaging in Patients With Inherited Retinal Degenerations

  • study on Retinitis Pigmentosa
  • open to healthy people ages 13 years and up

• Rural Dementia Caregiver Project

  • study on Depression and Stress, Psychological
  • open to healthy people ages 18 years and up

• Safety and Efficacy of T89 in the Prevention and Treatment of Adults With Acute Mountain Sickness (AMS)

  • study on Acute Mountain Sickness
  • open to healthy people ages 18-55

• Safety Net Support Use in California

  • open to healthy people ages 18 years and up

• Severe Asthma Research Program

  • study on Asthma
  • open to healthy people ages 6 years and up

• Short-Term Cardiovascular Effects of E-Cigarettes: Influence of E-Liquid pH

  • study on Cardiovascular Risk Factor and Nicotine Dependence
  • open to healthy people ages 21-70

• Sleep and Social Experiences Study 2

  • study on Sleep and Blood Pressure
  • open to healthy people ages 18-64

• Smoke-free Home Intervention in Permanent Supportive Housing

  • study on Smoking Cessation and Tobacco
  • open to healthy people ages 18 years and up

• Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents

  • study on Vaping and Cannabis
  • open to healthy people ages 13-17

• Sorting and Expression Profiling of Airway Cells From Humans (The SEARCH Study)

  • study on Asthma
  • open to healthy people ages 18-70

• SPL Insufficiency Syndrome (SPLIS): a SPLIS Observational Study and Patient Registry (International)

  • study on Sphingolipidoses and Enzyme Deficiency
  • open to healthy people

• Study of MK-4482 for Prevention of Coronavirus Disease 2019 (COVID-19) in Adults (MK-4482-013)

  • study on COVID-19
  • open to healthy people ages 18 years and up

• THC Crossover Study

  • study on THC and Cannabis
  • open to healthy people ages 21 years and up

• Tissue-specific Insulin Resistance in Obstructive Sleep Apnea: Role of Hypoxia

  • study on Obstructive Sleep Apnea and Sleep Apnea
  • open to healthy people ages 40-70

• Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain

  • study on Lower Back Pain and Pain
  • open to healthy people ages 21-85

• Transfusion Trigger After Operations in High Cardiac Risk Patients

  • study on Heart Attack and Coronary Revascularization
  • open to healthy people ages 18 years and up

• Transseptal vs Retrograde Aortic Ventricular Entry to Reduce Systemic Emboli

  • study on Neurocognitive Dysfunction
  • open to healthy people ages 18 years and up

• Treatment for Speech and Language in Primary Progressive Aphasia

  • study on Primary Progressive Aphasia and Dementia
  • open to healthy people

• Trial of Parkinson's And Zoledronic Acid

  • study on Parkinson's Disease and Osteoporosis
  • open to healthy people ages 60 years and up

• TrialNet Pathway to Prevention of T1D

  • study on Diabetes and Diabetes Type 1
  • open to healthy people ages 30 months to 45 years

• Understanding the Long-term Impact of COVID-19 in Adults

  • study on COVID-19
  • open to healthy people ages 18 years and up

• The Use of Lymph Node Biopsies to Support HIV Pathogenesis Studies

  • study on HIV/AIDS
  • open to healthy people ages 18-70

• The Use of Venlafaxine in Reducing Pain in Primary Total Knee Replacement

  • study on Acute Pain and Pain
  • open to healthy people ages 18-75

• The Use of Virtual Reality to Reduce Anxiety and Pain in Perioperative Settings

  • study on Perioperative Pain and Perioperative Anxiety
  • open to healthy people ages 18-75

• Using Electrophysiology to Index Non-invasive Brain Stimulation Effects on Reward System Functioning in Depression

  • study on Depression
  • open to healthy people ages 18-65

• Uterine Leiomyoma Treatment With Radiofrequency Ablation (ULTRA) Registry

  • study on Uterine Fibroids
  • open to healthy females ages 21 years and up

• Women Informed to Screen Depending on Measures of Risk (Wisdom Study)

  • study on Breast Cancer
  • open to healthy females ages 40-74