Clinical trials open to people under 18
(270 trials open to new patients)

• 4H Syndrome (1 open to new patients)
• AADC Deficiency (1 open to new patients)
• Abnormalities of Erythrocyte Differentiation or Function (1 open to new patients)
• Abnormalities of Platelets (1 open to new patients)
• Acanthamoeba Keratitis (1 open to new patients)
• Achondroplasia (1 open to new patients)
• ACL Injury (1 open to new patients)
• Acne (1 open to new patients)
• Acute Intermittent Porphyria (1 open to new patients)
• Acute Lung Injury (1 open to new patients)
• Acute Lymphoblastic Leukemia (18 open to new patients)
• Acute Myeloid Leukemia (10 open to new patients)
• Acute Respiratory Distress Syndrome (1 open to new patients)
• Adenovirus (2 open to new patients)
• ADLD (1 open to new patients)
• Adolescent Behavior (1 open to new patients)
• Adrenoleukodystrophy (1 open to new patients)
• Adrenomyeloneuropathy (1 open to new patients)
• Adverse Childhood Experiences (1 open to new patients)
• AGS (1 open to new patients)
• Aicardi Goutieres Syndrome (1 open to new patients)
• Aicardi Syndrome (1 open to new patients)
• Alagille Syndrome (1 open to new patients)
• Alcohol Use (1 open to new patients)
• ALD Gene Mutation (1 open to new patients)
• Alexander Disease (1 open to new patients)
• Alexanders Leukodystrophy (1 open to new patients)
• Allan-Herndon-Dudley Syndrome (1 open to new patients)
• Allogeneic Hematopoietic Cell Transplantation (2 open to new patients)
• Alpha Thalassemia (1 open to new patients)
• Alpha Thalassemia Major (1 open to new patients)
• ALSP (1 open to new patients)
• Amblyopia (1 open to new patients)
• AMN (1 open to new patients)
• Anemia (6 open to new patients)
• Anesthesia (2 open to new patients)
• Angiolipoma (1 open to new patients)
• Anti-NMDA Receptor Encephalitis (1 open to new patients)
• Anxiety (2 open to new patients)
• Aortic Stenosis (1 open to new patients)
• Aphasia (1 open to new patients)
• Arteriovenous Malformation (1 open to new patients)
• Astrocytoma (5 open to new patients)
• Atrial Flutter (1 open to new patients)
• Attention Training (1 open to new patients)
• Autoimmune Disease (1 open to new patients)
• Autoimmune Encephalitis (1 open to new patients)
• Autosomal Dominant Hypocalcemia (1 open to new patients)
• AxD (1 open to new patients)
• B-Cell Acute Lymphoblastic Leukemia (5 open to new patients)
• Beta Thalassemia (2 open to new patients)
• Blastic Plasmacytoid Dendritic Cell Neoplasm (1 open to new patients)
• Bleeding Disorder (1 open to new patients)
• Blood Cancer (2 open to new patients)
• Blood Coagulation Disorder (1 open to new patients)
• Bone Cancer (3 open to new patients)
• Bone Marrow Transplant (10 open to new patients)
• Borderline Intellectual Functioning (1 open to new patients)
• BPAN (1 open to new patients)
• Brain Cancer (3 open to new patients)
• Brain Hypoxia (2 open to new patients)
• Brain Tumor (5 open to new patients)
• Breast Cancer (1 open to new patients)
• Bronchiolitis Obliterans (3 open to new patients)
• C. Diff (1 open to new patients)
• CADASIL (1 open to new patients)
• Caesarean Section (1 open to new patients)
• Canavan Disease (3 open to new patients)
• Cancer, General (7 open to new patients)
• Cancer Harboring BRAF Alterations (1 open to new patients)
• Cancer Pediatric (1 open to new patients)
• CAR T-Cell Therapy (1 open to new patients)
• Carcinoma (7 open to new patients)
• Carcinoma In Situ (1 open to new patients)
• Cardiac Arrest (2 open to new patients)
• Cardiac Arrhythmia (1 open to new patients)
• Cardiomyopathy (2 open to new patients)
• Caregivers (2 open to new patients)
• Cataracts (1 open to new patients)
• Cavernous Hemangioma (1 open to new patients)
• Cavities (1 open to new patients)
• CBL Syndrome (1 open to new patients)
• Central Nervous System Carcinoma (1 open to new patients)
• Central Nervous System Neoplasms (3 open to new patients)
• Central Nervous System Tumor (3 open to new patients)
• Central Precocious Puberty (1 open to new patients)
• Cerebellar Ataxia (1 open to new patients)
• Cerebral Cavernous Malformations (1 open to new patients)
• Cerebral Palsy (1 open to new patients)
• Cerebrotendinous Xanthomatoses (1 open to new patients)
• Cerebrotendinous Xanthomatosis (1 open to new patients)
• Cervical Spine Injury (1 open to new patients)
• Charcot-Marie-Tooth Disease (1 open to new patients)
• Child Development (1 open to new patients)
• Chordoma (2 open to new patients)
• Choriocarcinoma (2 open to new patients)
• Chronic Granulomatous Disease (1 open to new patients)
• Chronic Kidney Disease (4 open to new patients)
• Chronic Lymphocytic Leukemia (2 open to new patients)
• Chronic Myeloid Leukemia (2 open to new patients)
• Chronic Thromboembolic Pulmonary Hypertension (1 open to new patients)
• Clavicle Fracture (1 open to new patients)
• Cockayne Syndrome (1 open to new patients)
• Cognitive Behavioral Therapy (1 open to new patients)
• Colitis (1 open to new patients)
• Colorectal Cancer (2 open to new patients)
• Colorectal Tumor (1 open to new patients)
• Common Variable Immunodeficiency (1 open to new patients)
• Communication (2 open to new patients)
• Congenital Heart Defects (4 open to new patients)
• Congenital Hyperinsulinism (1 open to new patients)
• Connective Tissue Disorder (1 open to new patients)
• COVID-19 (1 open to new patients)
• Craniopharyngioma (1 open to new patients)
• Crohn's Disease (5 open to new patients)
• CSF1R Gene Mutation (1 open to new patients)
• CTX (1 open to new patients)
• Cushing's Syndrome (1 open to new patients)
• Cystic Fibrosis (1 open to new patients)
• Cystic Nephroma (1 open to new patients)
• Cytomegalovirus (1 open to new patients)
• Deep Brain Stimulation (2 open to new patients)
• Delayed Sleep Phase (2 open to new patients)
• Depression (5 open to new patients)
• Desmoid Tumor (2 open to new patients)
• Developmental Dysphasia (1 open to new patients)
• Diabetes (11 open to new patients)
• Diabetes Type 1 (8 open to new patients)
• Diabetes Type 2 (3 open to new patients)
• Diffuse Alveolar Hemorrhage (1 open to new patients)
• Diffuse Large B-Cell Lymphoma (1 open to new patients)
• DIPG (3 open to new patients)
• Dislocated Shoulder (1 open to new patients)
• Dislocations (1 open to new patients)
• Disorders of Metabolism (1 open to new patients)
• Down Syndrome (2 open to new patients)
• Dravet Syndrome (3 open to new patients)
• Drug Use (1 open to new patients)
• Dysfunctional RVOT Conduit (1 open to new patients)
• Dysplasia (2 open to new patients)
• Dystonia (1 open to new patients)
• Early Labor (1 open to new patients)
• Eating Disorders (1 open to new patients)
• Eclampsia (1 open to new patients)
• Embryonal Carcinoma (1 open to new patients)
• End Stage Renal Disease (2 open to new patients)
• Endometrial Cancer (2 open to new patients)
• Enzyme Deficiency (1 open to new patients)
• Eosinophilic Duodenitis (1 open to new patients)
• Eosinophilic Esophagitis (1 open to new patients)
• Eosinophilic Gastritis (1 open to new patients)
• Eosinophilic Gastrointestinal Disease (1 open to new patients)
• Ependymoma (1 open to new patients)
• Epilepsy (6 open to new patients)
• Epileptic Encephalopathy (1 open to new patients)
• Epistaxis (1 open to new patients)
• Epithelioid Sarcoma (2 open to new patients)
• Epstein Barr Virus (1 open to new patients)
• Erythropoietic Protoporphyria (1 open to new patients)
• Esophageal Atresia (1 open to new patients)
• Essential Tremor (1 open to new patients)
• Ewing Sarcoma (3 open to new patients)
• Extracorporeal Membrane Oxygenation (1 open to new patients)
• Extragonadal Embryonal Carcinoma (1 open to new patients)
• Fabry Disease (1 open to new patients)
• Factor IX Deficiency (1 open to new patients)
• Fallopian Tube Cancer (1 open to new patients)
• Fatty Acid Oxidation Disorders (1 open to new patients)
• Fecal Microbiota Transplant (2 open to new patients)
• Female Reproductive System Neoplasm (1 open to new patients)
• Fetal Arrhythmia (1 open to new patients)
• Fetal Cardiac Disorder (1 open to new patients)
• Fibrodysplasia Ossificans Progressiva (1 open to new patients)
• Fibrolamellar Carcinoma (1 open to new patients)
• Fibrosis (1 open to new patients)
• Fistula (1 open to new patients)
• Fractured Spine (1 open to new patients)
• Fulminant Hepatic Failure (1 open to new patients)
• GALC Deficiency (1 open to new patients)
• Ganglioneuroblastoma (2 open to new patients)
• Ganglioneuroma (1 open to new patients)
• Gangliosidoses (1 open to new patients)
• Gastrointestinal Bleeding (1 open to new patients)
• Gaucher Disease (2 open to new patients)
• Genital Neoplasms (1 open to new patients)
• Germ Cell Tumor (2 open to new patients)
• Glioblastoma (4 open to new patients)
• Glioma (15 open to new patients)
• Globoid Leukodystrophy (1 open to new patients)
• Glomerulonephritis (1 open to new patients)
• Glucocerebrosidase Deficiency Disease (1 open to new patients)
• GM1 Gangliosidosis (1 open to new patients)
• GM2 Gangliosidosis (1 open to new patients)
• gMG (1 open to new patients)
• Graft Versus Host Disease (3 open to new patients)
• Gut Microbiome (1 open to new patients)
• HBSL (1 open to new patients)
• Headache (1 open to new patients)
• Hearing Disorders (1 open to new patients)
• Hearing Loss (1 open to new patients)
• Heart Block Complete (1 open to new patients)
• Heart Block Second Degree (1 open to new patients)
• Heart Disease (4 open to new patients)
• Heart Transplant (1 open to new patients)
• Hematologic Disease (2 open to new patients)
• Hematologic Malignancy (4 open to new patients)
• Hematologic Neoplasms (4 open to new patients)
• Hematopoietic and Lymphatic System Neoplasm (1 open to new patients)
• Hematopoietic and Lymphoid Cell Neoplasm (2 open to new patients)
• Hematopoietic Cell Transplantation (7 open to new patients)
• HEMNOS (1 open to new patients)
• Hemolytic-Uremic Syndrome (1 open to new patients)
• Hemophilia (1 open to new patients)
• Hepatic Encephalopathy (1 open to new patients)
• Hepatic Veno-Occlusive Disease (1 open to new patients)
• Hepatitis (1 open to new patients)
• Hepatitis A (1 open to new patients)
• Hepatitis B (1 open to new patients)
• Hepatoblastoma (3 open to new patients)
• Hepatocellular Cancer (3 open to new patients)
• Hidradenitis Suppurativa (2 open to new patients)
• High Blood Pressure (6 open to new patients)
• Histiocytic Disorders (1 open to new patients)
• HIV/AIDS (1 open to new patients)
• Hodgkin's Lymphoma (2 open to new patients)
• Hunter Syndrome (4 open to new patients)
• Hydrops Fetalis (1 open to new patients)
• Hyperoxaluria (1 open to new patients)
• Hypertensive Disorders of Pregnancy (1 open to new patients)
• Hypochondroplasia (2 open to new patients)
• Hypoplastic Left Heart Syndrome (1 open to new patients)
• Hypoxia (2 open to new patients)
• Hypoxic-Ischemic Encephalopathy (1 open to new patients)
• IC-MPGN (1 open to new patients)
• IDH1 Gene Mutation (1 open to new patients)
• IDH2 Gene Mutation (1 open to new patients)
• Immune Dysregulation (1 open to new patients)
• Immune Regulatory Disorder (1 open to new patients)
• Immunodeficiency (8 open to new patients)
• Immunotherapy (4 open to new patients)
• Induced Hypothermia (1 open to new patients)
• Inflammatory Bowel Disease (9 open to new patients)
• INI1-negative Tumors (1 open to new patients)
• Insomnia (1 open to new patients)
• Intellectual Disability (2 open to new patients)
• Interstitial Lung Disease (2 open to new patients)
• Intracranial Hemorrhage (1 open to new patients)
• JCML (1 open to new patients)
• Joint Instability (1 open to new patients)
• Juvenile Myelomonocytic Leukemia (3 open to new patients)
• Kidney Cancer (2 open to new patients)
• Kidney Disease (4 open to new patients)
• Kidney Medullary Carcinoma (2 open to new patients)
• Kidney Neoplasm (2 open to new patients)
• Kidney Oncocytoma (1 open to new patients)
• Kidney Transplant (1 open to new patients)
• Krabbe Disease (1 open to new patients)
• Labrune Syndrome (1 open to new patients)
• Langerhans Cell Histiocytosis (3 open to new patients)
• LBSL (1 open to new patients)
• LCC (1 open to new patients)
• Lennox-Gastaut Syndrome (1 open to new patients)
• Leukemia (22 open to new patients)
• Leukodystrophy (1 open to new patients)
• Leukoencephalopathies (1 open to new patients)
• LGI1-Antibody Encephalitis (1 open to new patients)
• Life Adversity (2 open to new patients)
• Liver Cancer (4 open to new patients)
• Liver Disease (2 open to new patients)
• Liver Failure (1 open to new patients)
• Liver Injury (1 open to new patients)
• Liver Transplant (3 open to new patients)
• Locally Advanced Malignant Solid Neoplasm (1 open to new patients)
• Loneliness (1 open to new patients)
• Lupus (2 open to new patients)
• Lymphoma (22 open to new patients)
• Lymphoproliferative Disorders (2 open to new patients)
• Machado–Joseph Disease (1 open to new patients)
• Malignant Neoplasm (4 open to new patients)
• Meditation (1 open to new patients)
• Medulloblastoma (3 open to new patients)
• Melanocytic Neoplasm (1 open to new patients)
• Meningioma (1 open to new patients)
• Mental Disorder (1 open to new patients)
• Mental Health (2 open to new patients)
• Mesoblastic Nephroma (2 open to new patients)
• Metabolomic Profile (1 open to new patients)
• Metachromatic Leukodystrophy (1 open to new patients)
• Metanephric Adenofibroma (1 open to new patients)
• Metanephric Adenoma (1 open to new patients)
• Metanephric Stromal Tumor (1 open to new patients)
• Metanephric Tumor (1 open to new patients)
• Metastatic Osteosarcoma (1 open to new patients)
• Migraine (1 open to new patients)
• MLC1 (1 open to new patients)
• MLD (1 open to new patients)
• Mucopolysaccharidosis (9 open to new patients)
• Mucopolysaccharidosis Type I (3 open to new patients)
• Mucopolysaccharidosis Type VI (1 open to new patients)
• Mucopolysaccharidosis Type VII (1 open to new patients)
• Multiple Myeloma (1 open to new patients)
• Multiple Organ Dysfunction Syndrome (1 open to new patients)
• Multiple Sulfatase Deficiency (1 open to new patients)
• Myasthenia Gravis (2 open to new patients)
• Myelodysplastic Syndrome (6 open to new patients)
• Myeloproliferative Neoplasms (1 open to new patients)
• Myopia (1 open to new patients)
• Nasopharyngeal Cancer (1 open to new patients)
• Nausea (1 open to new patients)
• Neoplasms (28 open to new patients)
• Neoplasm of Uncertain Malignant Potential (1 open to new patients)
• Neuroblastoma (12 open to new patients)
• Neuroectodermal Tumors (1 open to new patients)
• Neuroendocrine Carcinoma (1 open to new patients)
• Neuroendocrine Neoplasm (1 open to new patients)
• Neuroendocrine Tumor (1 open to new patients)
• Neurofibromatosis (2 open to new patients)
• Neuroimaging (1 open to new patients)
• Neurologic Disorder (1 open to new patients)
• Neuropathy (1 open to new patients)
• NGLY1 Deficiency (1 open to new patients)
• Non-Hodgkin Lymphoma (6 open to new patients)
• Obesity (3 open to new patients)
• Ossifying Renal Tumor of Infancy (1 open to new patients)
• Osteochondral Defect (1 open to new patients)
• Osteoid Osteoma (1 open to new patients)
• Osteosarcoma (3 open to new patients)
• Ovarian Cancer (3 open to new patients)
• Ovarian Embryonal Carcinoma (1 open to new patients)
• Ovarian Tumor (2 open to new patients)
• Pancreatic Cancer (2 open to new patients)
• Pancreatic Ductal Adenocarcinoma (1 open to new patients)
• Pancreatic Neoplasms (2 open to new patients)
• Pancreatitis (1 open to new patients)
• Parent-Child Relations (1 open to new patients)
• Parkinson's Disease (1 open to new patients)
• Patient Satisfaction (1 open to new patients)
• Pelizaeus-Merzbacher Disease (1 open to new patients)
• Peritoneal Cancer (1 open to new patients)
• Peroxisomal Biogenesis Disorder (1 open to new patients)
• Pheochromocytoma (1 open to new patients)
• Platelet Disorder (1 open to new patients)
• PLP1 Null Syndrome (1 open to new patients)
• Pneumonia (1 open to new patients)
• Pompe Disease (2 open to new patients)
• Porphyria (1 open to new patients)
• Post-Traumatic Stress Disorder (1 open to new patients)
• Postpartum Depression (1 open to new patients)
• PPAP (1 open to new patients)
• Preeclampsia (1 open to new patients)
• Pregnancy (2 open to new patients)
• Premature Birth (2 open to new patients)
• Prenatal Stress (1 open to new patients)
• Primary Hyperparathyroidism (1 open to new patients)
• Primary Immunodeficiency Diseases (4 open to new patients)
• Primitive Neuroectodermal Tumor (1 open to new patients)
• Procedural Anxiety (1 open to new patients)
• Procedural Pain (1 open to new patients)
• Psychotic Disorders (1 open to new patients)
• Pulmonary Arterial Hypertension (4 open to new patients)
• Pulmonary Hypertension (5 open to new patients)
• Pulmonary Regurgitation (1 open to new patients)
• Pulmonary Valve Degeneration (1 open to new patients)
• Pulmonary Vascular Resistance Abnormality (1 open to new patients)
• Rare Bleeding Disorder (1 open to new patients)
• Recurrent Osteosarcoma (2 open to new patients)
• Refractory Osteosarcoma (2 open to new patients)
• Refractory Tumor (1 open to new patients)
• Refsum Disease (1 open to new patients)
• Renal Cell Carcinoma (1 open to new patients)
• Respiratory Distress Syndrome (1 open to new patients)
• Retinal Degeneration (1 open to new patients)
• Retinal Diseases (1 open to new patients)
• Retinal Dystrophy (3 open to new patients)
• Retinitis Pigmentosa (3 open to new patients)
• Retinopathy of Prematurity (1 open to new patients)
• Rett Syndrome (1 open to new patients)
• Rhabdoid Tumor (3 open to new patients)
• Rhabdomyosarcoma (2 open to new patients)
• Rheumatic Joint Disease (1 open to new patients)
• Risk-Taking (1 open to new patients)
• RSV (1 open to new patients)
• Salla Disease (1 open to new patients)
• Sanfilippo Syndrome (2 open to new patients)
• Sarcoma (6 open to new patients)
• Schizophrenia (1 open to new patients)
• Sedation (1 open to new patients)
• Seizures (2 open to new patients)
• Self Efficacy (1 open to new patients)
• Seminoma (1 open to new patients)
• Sensorineural Hearing Loss (1 open to new patients)
• Sepsis (2 open to new patients)
• Septic Shock (1 open to new patients)
• Severe Combined Immunodeficiency (3 open to new patients)
• Shock (1 open to new patients)
• Short Bowel Syndrome (1 open to new patients)
• Shoulder Instability (1 open to new patients)
• Sialic Storage Disease (1 open to new patients)
• Sickle Cell Anemia (4 open to new patients)
• Single Ventricle Heart Disease (1 open to new patients)
• Sjögren (1 open to new patients)
• Sjögren-Larsson Syndrome (1 open to new patients)
• Sjögren Syndrome (1 open to new patients)
• Skin Cancer/Melanoma (4 open to new patients)
• Sleep Disorders (1 open to new patients)
• Small Lymphocytic Lymphoma (1 open to new patients)
• SMARCA4-deficient Malignant Tumors (1 open to new patients)
• Solid Neoplasm (8 open to new patients)
• Solid Tumor (9 open to new patients)
• Spastic Cerebral Palsy (1 open to new patients)
• Sphingolipidoses (1 open to new patients)
• Spinal Column Tumor (1 open to new patients)
• Spinal Cord Injury (1 open to new patients)
• Spinal Paralysis (1 open to new patients)
• Spine Fusion (1 open to new patients)
• Spinocerebellar Ataxia (1 open to new patients)
• SPLIS (2 open to new patients)
• Stem Cell Transplant (9 open to new patients)
• Stress (1 open to new patients)
• Stroke (1 open to new patients)
• Stromal Neoplasm (1 open to new patients)
• Sturge-Weber Syndrome (1 open to new patients)
• Subluxations (1 open to new patients)
• Substance Abuse (2 open to new patients)
• Supratentorial Neoplasm (1 open to new patients)
• Supraventricular Tachycardia (1 open to new patients)
• T Cell Lymphoma (2 open to new patients)
• Tachycardia (1 open to new patients)
• Tay-Sachs Disease (1 open to new patients)
• TBCK-Related Intellectual Disability Syndrome (1 open to new patients)
• Telangiectasia (2 open to new patients)
• Teratoma (3 open to new patients)
• Testicular Cancer (1 open to new patients)
• Thalassemia (2 open to new patients)
• Thrombophilia (1 open to new patients)
• Thrombosis (1 open to new patients)
• Thrombotic Microangiopathies (1 open to new patients)
• Thyroid Cancer (1 open to new patients)
• Transplants (6 open to new patients)
• TUBB4A-Related Leukodystrophy (1 open to new patients)
• Ulcerative Colitis (6 open to new patients)
• Unresectable Malignant Solid Neoplasm (1 open to new patients)
• Van Der Knapp Disease (1 open to new patients)
• Vanishing White Matter Disease (1 open to new patients)
• Vascular Disease (1 open to new patients)
• Vascular Malformation (1 open to new patients)
• Vomiting (1 open to new patients)
• Von Willebrand Disease (1 open to new patients)
• Wheezing (1 open to new patients)
• Wheezing Lower Respiratory Illness (1 open to new patients)
• White Matter Disease (1 open to new patients)
• Wilms Tumor (3 open to new patients)
• Wolman Disease (1 open to new patients)
• X-Linked Intellectual Disability (1 open to new patients)
• X-Linked Protoporphyria (1 open to new patients)
• Zellweger Syndrome (1 open to new patients)