Clinical trials open to people under 18
(263 trials open to new patients)

• 4H Syndrome (1 open to new patients)
• AADC Deficiency (1 open to new patients)
• Abnormalities of Erythrocyte Differentiation or Function (1 open to new patients)
• Abnormalities of Platelets (1 open to new patients)
• Abortion (1 open to new patients)
• Acanthamoeba Keratitis (1 open to new patients)
• Achondroplasia (1 open to new patients)
• ACL Injury (1 open to new patients)
• Acute Intermittent Porphyria (1 open to new patients)
• Acute Kidney Injury (1 open to new patients)
• Acute Lymphoblastic Leukemia (13 open to new patients)
• Acute Myeloid Leukemia (7 open to new patients)
• Acute Respiratory Distress Syndrome (1 open to new patients)
• Adenovirus (2 open to new patients)
• ADLD (1 open to new patients)
• Adolescent Behavior (1 open to new patients)
• Adrenoleukodystrophy (1 open to new patients)
• Adrenomyeloneuropathy (1 open to new patients)
• Aicardi–Goutières syndrome (1 open to new patients)
• Alagille Syndrome (1 open to new patients)
• Alcohol Use (1 open to new patients)
• ALD Gene Mutation (1 open to new patients)
• Alexander Disease (1 open to new patients)
• Alexanders Leukodystrophy (1 open to new patients)
• Allan-Herndon-Dudley Syndrome (1 open to new patients)
• Allogeneic Hematopoietic Cell Transplantation (1 open to new patients)
• Alpha Thalassemia (1 open to new patients)
• Alpha Thalassemia Major (1 open to new patients)
• ALSP (1 open to new patients)
• Amblyopia (4 open to new patients)
• AMN (1 open to new patients)
• Androgen Insensitivity Syndrome (1 open to new patients)
• Anemia (5 open to new patients)
• Anesthesia (2 open to new patients)
• Anorexia (1 open to new patients)
• Anti-NMDA Receptor Encephalitis (1 open to new patients)
• Anti-Synthetase Syndrome (1 open to new patients)
• Anxiety (1 open to new patients)
• Aortic Stenosis (3 open to new patients)
• Arteriovenous Malformation (1 open to new patients)
• Arthritis (1 open to new patients)
• Astroblastoma (1 open to new patients)
• Astrocytoma (6 open to new patients)
• Attention-Deficit/Hyperactivity Disorder (2 open to new patients)
• Autism (1 open to new patients)
• Autoimmune Disease (2 open to new patients)
• Autoimmune Encephalitis (1 open to new patients)
• Autosomal Dominant Polycystic Kidney Disease (1 open to new patients)
• AxD (1 open to new patients)
• B-Cell Acute Lymphoblastic Leukemia (5 open to new patients)
• Beta Thalassemia (1 open to new patients)
• Bladder Cancer (1 open to new patients)
• Blastic Plasmacytoid Dendritic Cell Neoplasm (1 open to new patients)
• Bleeding Disorder (1 open to new patients)
• Blindness (1 open to new patients)
• Blood Cancer (2 open to new patients)
• Bone Cancer (3 open to new patients)
• Bone Density (1 open to new patients)
• Bone Marrow Transplant (10 open to new patients)
• Borderline Intellectual Functioning (1 open to new patients)
• BPAN (1 open to new patients)
• Brain Cancer (2 open to new patients)
• Brain Hypoxia (2 open to new patients)
• Brain Tumor (5 open to new patients)
• BRCA Gene Rearrangement (1 open to new patients)
• Breast Cancer (2 open to new patients)
• Bronchiolitis Obliterans (2 open to new patients)
• C. Diff (1 open to new patients)
• CADASIL (1 open to new patients)
• Caesarean Section (2 open to new patients)
• Calcium Release Deficiency Syndrome (1 open to new patients)
• Calcium Release Deficiency Syndrome (CRDS) (1 open to new patients)
• Canavan Disease (2 open to new patients)
• Cancer, General (8 open to new patients)
• Cancer Harboring BRAF Alterations (1 open to new patients)
• Cancer Liver (1 open to new patients)
• Cancer of Neck (1 open to new patients)
• Cancer Prostate (1 open to new patients)
• CAR T-Cell Therapy (1 open to new patients)
• Carcinoma (1 open to new patients)
• Carcinoma In Situ (1 open to new patients)
• Cardiac Arrest (2 open to new patients)
• Cardiac Arrhythmia (1 open to new patients)
• Cardiomyopathy (2 open to new patients)
• Cardiovascular Disease (2 open to new patients)
• Cataracts (1 open to new patients)
• CBL Syndrome (1 open to new patients)
• Central Nervous System Neoplasms (3 open to new patients)
• Central Nervous System Tumor (3 open to new patients)
• Central Precocious Puberty (1 open to new patients)
• Cerebral Palsy (1 open to new patients)
• Cerebrotendinous Xanthomatoses (1 open to new patients)
• Cerebrotendinous Xanthomatosis (1 open to new patients)
• Cervical Cancer (1 open to new patients)
• Cervical Spine Injury (1 open to new patients)
• Charcot-Marie-Tooth Disease (2 open to new patients)
• Child Development (1 open to new patients)
• Cholangiocarcinoma (1 open to new patients)
• Cholesterol (2 open to new patients)
• Choriocarcinoma (2 open to new patients)
• Chronic Granulomatous Disease (1 open to new patients)
• Chronic Kidney Disease (3 open to new patients)
• Chronic Myeloid Leukemia (1 open to new patients)
• Chronic Thromboembolic Pulmonary Hypertension (1 open to new patients)
• CLOVES Syndrome (1 open to new patients)
• Cockayne Syndrome (1 open to new patients)
• Cognitive Behavioral Therapy (1 open to new patients)
• Colitis (1 open to new patients)
• Colon Cancer (2 open to new patients)
• Colorectal Cancer (3 open to new patients)
• Colorectal Tumor (3 open to new patients)
• Common Variable Immunodeficiency (1 open to new patients)
• Communication (2 open to new patients)
• Cone-Rod Dystrophy (1 open to new patients)
• Congenital Heart Defects (4 open to new patients)
• Congenital Hyperinsulinism (1 open to new patients)
• Connective Tissue Disorder (1 open to new patients)
• COVID-19 (1 open to new patients)
• Craniopharyngioma (1 open to new patients)
• Crohn's Disease (6 open to new patients)
• CSF1R Gene Mutation (1 open to new patients)
• CTX (1 open to new patients)
• Cushing's Syndrome (1 open to new patients)
• Cystic Fibrosis (1 open to new patients)
• Cytomegalovirus (1 open to new patients)
• Deafness and Blindness (1 open to new patients)
• Deep Brain Stimulation (2 open to new patients)
• Delayed Sleep Phase (2 open to new patients)
• Dementia (1 open to new patients)
• Depression (4 open to new patients)
• Dermatomyositis (1 open to new patients)
• Desmoid Tumor (2 open to new patients)
• Developmental and Epileptic Encephalopathy (1 open to new patients)
• Developmental Dysphasia (1 open to new patients)
• Diabetes (11 open to new patients)
• Diabetes Type 1 (7 open to new patients)
• Diabetes Type 2 (3 open to new patients)
• Diffuse Alveolar Hemorrhage (1 open to new patients)
• DIPG (3 open to new patients)
• Dislocated Shoulder (1 open to new patients)
• Dislocations (1 open to new patients)
• Disorders of Metabolism (1 open to new patients)
• Down Syndrome (3 open to new patients)
• Dravet Syndrome (4 open to new patients)
• Dysfunctional RVOT Conduit (1 open to new patients)
• Dyslipidemia (2 open to new patients)
• Dysplasia (2 open to new patients)
• Dystonia (1 open to new patients)
• Eclampsia (1 open to new patients)
• Embryonal Carcinoma (1 open to new patients)
• Embryonal Tumor With Multilayered Rosettes (1 open to new patients)
• Emotional Regulation (1 open to new patients)
• End Stage Renal Disease (2 open to new patients)
• Endometrial Cancer (3 open to new patients)
• Enzyme Deficiency (1 open to new patients)
• Eosinophilic Esophagitis (1 open to new patients)
• Ependymoma (2 open to new patients)
• Epilepsy (8 open to new patients)
• Epileptic Encephalopathy (2 open to new patients)
• Epistaxis (1 open to new patients)
• Epstein Barr Virus (1 open to new patients)
• Erdheim-Chester Disease (1 open to new patients)
• Erythropoietic Protoporphyria (2 open to new patients)
• Esophageal Cancer (1 open to new patients)
• Essential Tremor (1 open to new patients)
• Ewing Sarcoma (3 open to new patients)
• Exercise (1 open to new patients)
• Extracorporeal Membrane Oxygenation (1 open to new patients)
• Extragonadal Embryonal Carcinoma (1 open to new patients)
• Fabry Disease (1 open to new patients)
• Factor IX Deficiency (1 open to new patients)
• Fallopian Tube Cancer (1 open to new patients)
• Fatty Acid Oxidation Disorders (1 open to new patients)
• Fecal Microbiota Transplant (1 open to new patients)
• Female Reproductive System Neoplasm (1 open to new patients)
• Fetal Cardiac Disorder (1 open to new patients)
• Fibrodysplasia Ossificans Progressiva (1 open to new patients)
• Fibrolamellar Carcinoma (1 open to new patients)
• Fibrosis (1 open to new patients)
• Focal Segmental Glomerulosclerosis (1 open to new patients)
• Food Insecurity (1 open to new patients)
• Food Insecurity Among Children (1 open to new patients)
• Fractured Spine (1 open to new patients)
• GALC Deficiency (1 open to new patients)
• Ganglioneuroblastoma (3 open to new patients)
• Ganglioneuroma (1 open to new patients)
• Gangliosidoses (1 open to new patients)
• Gastrointestinal Bleeding (1 open to new patients)
• Gaucher Disease (2 open to new patients)
• Germ Cell Tumor (3 open to new patients)
• Glioblastoma (5 open to new patients)
• Glioma (17 open to new patients)
• Globoid Leukodystrophy (1 open to new patients)
• Glomerulonephritis (2 open to new patients)
• Glucocerebrosidase Deficiency Disease (1 open to new patients)
• Glucose Intolerance (1 open to new patients)
• GM2 Gangliosidosis (1 open to new patients)
• gMG (1 open to new patients)
• Graft Versus Host Disease (2 open to new patients)
• Growth Hormone Deficiency (2 open to new patients)
• Gut Microbiome (1 open to new patients)
• HBSL (1 open to new patients)
• Head and Neck Cancer (1 open to new patients)
• Head and Neck Tumor (1 open to new patients)
• Headache (1 open to new patients)
• Hearing Disorders (1 open to new patients)
• Hearing Loss (2 open to new patients)
• Heart Block Complete (1 open to new patients)
• Heart Block Second Degree (1 open to new patients)
• Heart Failure (3 open to new patients)
• Heart Transplant (1 open to new patients)
• Hematologic Disease (1 open to new patients)
• Hematologic Malignancy (2 open to new patients)
• Hematologic Neoplasms (5 open to new patients)
• Hematopoietic and Lymphoid Cell Neoplasm (2 open to new patients)
• Hematopoietic Cell Transplantation (5 open to new patients)
• HEMNOS (1 open to new patients)
• Hemophilia (1 open to new patients)
• Hepatoblastoma (3 open to new patients)
• Hepatocellular Cancer (4 open to new patients)
• HGG (1 open to new patients)
• Hidradenitis Suppurativa (2 open to new patients)
• High Blood Pressure (3 open to new patients)
• Histiocytic Disorders (1 open to new patients)
• Histiocytic Disorders, Malignant (1 open to new patients)
• HIV/AIDS (1 open to new patients)
• Hodgkin's Lymphoma (2 open to new patients)
• Hunter Syndrome (3 open to new patients)
• Hyperoxaluria (1 open to new patients)
• Hypertensive Disorders of Pregnancy (1 open to new patients)
• Hypochondroplasia (2 open to new patients)
• Hypogonadism, Male (1 open to new patients)
• Hypoplastic Left Heart Syndrome (1 open to new patients)
• Hypothyroidism (1 open to new patients)
• Hypoxia (2 open to new patients)
• Hypoxic-Ischemic Encephalopathy (1 open to new patients)
• IC-MPGN (1 open to new patients)
• IDH1 Gene Mutation (1 open to new patients)
• IDH2 Gene Mutation (1 open to new patients)
• Idiopathic Short Stature (1 open to new patients)
• Immune Regulatory Disorder (1 open to new patients)
• Immunodeficiency (8 open to new patients)
• Immunotherapy (6 open to new patients)
• Induced Hypothermia (1 open to new patients)
• Inflammatory Bowel Disease (11 open to new patients)
• Insomnia (1 open to new patients)
• Insulin Resistance (1 open to new patients)
• Intellectual Disability (2 open to new patients)
• Interstitial Lung Disease (2 open to new patients)
• Intracranial Hemorrhage (1 open to new patients)
• JCML (1 open to new patients)
• Joint Instability (1 open to new patients)
• Juvenile Dermatomyositis (1 open to new patients)
• Juvenile Myelomonocytic Leukemia (3 open to new patients)
• Juvenile Myositis (1 open to new patients)
• Juvenile Polymyositis (1 open to new patients)
• Juvenile Xanthogranuloma (1 open to new patients)
• Kidney Cancer (2 open to new patients)
• Kidney Disease (5 open to new patients)
• Kidney Neoplasm (2 open to new patients)
• Kidney Transplant (1 open to new patients)
• Klippel Trenaunay Syndrome (1 open to new patients)
• Krabbe Disease (1 open to new patients)
• Labor and Delivery Complication (1 open to new patients)
• Labrune Syndrome (1 open to new patients)
• Langerhans Cell Histiocytosis (4 open to new patients)
• Laryngeal Cancer (1 open to new patients)
• LBSL (1 open to new patients)
• LCC (1 open to new patients)
• Leber Congenital Amaurosis (1 open to new patients)
• Leber Congenital Amaurosis 10 (1 open to new patients)
• Lennox-Gastaut Syndrome (2 open to new patients)
• Leukemia (21 open to new patients)
• Leukodystrophy (1 open to new patients)
• Leukoencephalopathies (1 open to new patients)
• LGG (1 open to new patients)
• LGI1-Antibody Encephalitis (1 open to new patients)
• Liver Cancer (5 open to new patients)
• Liver Disease (3 open to new patients)
• Liver Transplant (2 open to new patients)
• Localized Osteosarcoma (1 open to new patients)
• Locally Advanced Malignant Solid Neoplasm (1 open to new patients)
• Lung Cancer (1 open to new patients)
• Lung Tumor (1 open to new patients)
• Lupus (2 open to new patients)
• Lymphatic Malformations (2 open to new patients)
• Lymphoma (17 open to new patients)
• Lymphoproliferative Disorders (2 open to new patients)
• Malignant Neoplasm (3 open to new patients)
• Mantle Cell Lymphoma (1 open to new patients)
• Meditation (1 open to new patients)
• Medulloblastoma (4 open to new patients)
• Melanocytic Neoplasm (1 open to new patients)
• Mental Health (2 open to new patients)
• Mesoblastic Nephroma (1 open to new patients)
• Metachromatic Leukodystrophy (1 open to new patients)
• Metastatic Osteosarcoma (2 open to new patients)
• Migraine (1 open to new patients)
• Minimal Change Disease (1 open to new patients)
• Mismatch Repair Deficiency (1 open to new patients)
• MLC1 (1 open to new patients)
• MLD (1 open to new patients)
• Mucopolysaccharidosis (7 open to new patients)
• Mucopolysaccharidosis Type I (2 open to new patients)
• Mucopolysaccharidosis Type VI (1 open to new patients)
• Mucopolysaccharidosis Type VII (1 open to new patients)
• Multiple Myeloma (1 open to new patients)
• Multiple Organ Dysfunction Syndrome (1 open to new patients)
• Multiple Sulfatase Deficiency (1 open to new patients)
• Myasthenia Gravis (2 open to new patients)
• Myelodysplastic Syndrome (4 open to new patients)
• Myelofibrosis (1 open to new patients)
• Myeloproliferative Disorders (1 open to new patients)
• Myeloproliferative Neoplasms (2 open to new patients)
• Myopathy (2 open to new patients)
• Myopia (1 open to new patients)
• Nasopharyngeal Cancer (2 open to new patients)
• Nausea (1 open to new patients)
• Necrotizing Enterocolitis (1 open to new patients)
• Neoplasms (14 open to new patients)
• Neoplasm of Uncertain Malignant Potential (1 open to new patients)
• Neuroblastoma (9 open to new patients)
• Neurodegenerative Disease (1 open to new patients)
• Neuroendocrine Neoplasm (1 open to new patients)
• Neuroendocrine Tumor (2 open to new patients)
• Neurofibromatosis (1 open to new patients)
• Neurologic Disorder (1 open to new patients)
• Neurological Manifestations (1 open to new patients)
• Neuropathy (1 open to new patients)
• NGLY1 Deficiency (1 open to new patients)
• Non-Hodgkin Lymphoma (4 open to new patients)
• Non-Small Cell Lung Cancer (1 open to new patients)
• Obesity (3 open to new patients)
• Obsessive-Compulsive Disorder (2 open to new patients)
• Obstetric Complication (2 open to new patients)
• Osteochondral Defect (1 open to new patients)
• Osteoid Osteoma (1 open to new patients)
• Osteosarcoma (3 open to new patients)
• Ovarian Cancer (3 open to new patients)
• Ovarian Embryonal Carcinoma (1 open to new patients)
• Ovarian Tumor (2 open to new patients)
• Pancreatic Cancer (3 open to new patients)
• Pancreatic Ductal Adenocarcinoma (1 open to new patients)
• Pancreatic Neoplasms (2 open to new patients)
• Pancreatitis (1 open to new patients)
• Parent-Child Relations (1 open to new patients)
• Parkinson's Disease (1 open to new patients)
• Pelizaeus-Merzbacher Disease (1 open to new patients)
• Peritoneal Cancer (1 open to new patients)
• Peroxisomal Biogenesis Disorder (1 open to new patients)
• Pheochromocytoma (1 open to new patients)
• PIK3CA Mutation (2 open to new patients)
• PIK3CA-Related Overgrowth Spectrum (1 open to new patients)
• Platelet Disorder (1 open to new patients)
• PLP1 Null Syndrome (1 open to new patients)
• Pompe Disease (2 open to new patients)
• Porphyria (2 open to new patients)
• PPAP (1 open to new patients)
• Preeclampsia (1 open to new patients)
• Premature Birth (1 open to new patients)
• Preterm Delivery (1 open to new patients)
• Primary Hyperparathyroidism (1 open to new patients)
• Primary Immunodeficiency Diseases (5 open to new patients)
• Primary Myelofibrosis (1 open to new patients)
• Primitive Neuroectodermal Tumor (1 open to new patients)
• Procedural Anxiety (1 open to new patients)
• Procedural Pain (1 open to new patients)
• Prostate Cancer (1 open to new patients)
• Pulmonary Arterial Hypertension (2 open to new patients)
• Pulmonary Hypertension (2 open to new patients)
• Pulmonary Regurgitation (1 open to new patients)
• Pulmonary Valve Degeneration (1 open to new patients)
• Rare Bleeding Disorder (1 open to new patients)
• Rectal Cancer (2 open to new patients)
• Recurrent Osteosarcoma (1 open to new patients)
• Refractory Osteosarcoma (1 open to new patients)
• Refsum Disease (1 open to new patients)
• Respiratory Distress Syndrome (1 open to new patients)
• Retinal Degeneration (1 open to new patients)
• Retinal Disease (2 open to new patients)
• Retinal Dystrophy (2 open to new patients)
• Retinitis Pigmentosa (3 open to new patients)
• Rett Syndrome (1 open to new patients)
• Rhabdomyosarcoma (2 open to new patients)
• Rheumatic Joint Disease (1 open to new patients)
• Risk-Taking (1 open to new patients)
• Rosai-Dorfman Disease (1 open to new patients)
• RSV (1 open to new patients)
• Salla Disease (1 open to new patients)
• Sanfilippo Syndrome (1 open to new patients)
• Sarcoma (5 open to new patients)
• Scoliosis (1 open to new patients)
• Secondary Osteosarcoma (1 open to new patients)
• Sedation (1 open to new patients)
• Seizures (7 open to new patients)
• Self Efficacy (1 open to new patients)
• Seminoma (1 open to new patients)
• Sensation Disorders (1 open to new patients)
• Sensorineural Hearing Loss (1 open to new patients)
• Sepsis (2 open to new patients)
• Septic Shock (1 open to new patients)
• Severe Combined Immunodeficiency (2 open to new patients)
• Shock (1 open to new patients)
• Short Bowel Syndrome (1 open to new patients)
• Shoulder Instability (1 open to new patients)
• Sialic Storage Disease (1 open to new patients)
• Sickle Cell Anemia (4 open to new patients)
• Single Ventricle Heart Disease (1 open to new patients)
• Sjögren (1 open to new patients)
• Sjögren-Larsson Syndrome (1 open to new patients)
• Sjögren Syndrome (1 open to new patients)
• Skin Cancer/Melanoma (4 open to new patients)
• Sleep Disorders (1 open to new patients)
• Soft Tissue Sarcoma (1 open to new patients)
• Solid Neoplasm (6 open to new patients)
• Solid Tumor (10 open to new patients)
• Spastic Cerebral Palsy (1 open to new patients)
• Sphingolipidoses (1 open to new patients)
• Spinal Column Tumor (1 open to new patients)
• Spinal Cord Injury (1 open to new patients)
• Spinal Paralysis (1 open to new patients)
• Spine Fusion (1 open to new patients)
• SPLIS (2 open to new patients)
• Stargardt Disease (1 open to new patients)
• Stem Cell Transplant (10 open to new patients)
• STGD1 (1 open to new patients)
• Stomach Cancer (1 open to new patients)
• Stress (1 open to new patients)
• Stroke (1 open to new patients)
• Stromal Neoplasm (1 open to new patients)
• Sturge-Weber Syndrome (1 open to new patients)
• Subluxations (1 open to new patients)
• Substance Abuse (1 open to new patients)
• T Cell Lymphoma (2 open to new patients)
• TBCK-Related Intellectual Disability Syndrome (1 open to new patients)
• Telangiectasia (1 open to new patients)
• Teratoma (3 open to new patients)
• Testicular Cancer (2 open to new patients)
• Tetralogy of Fallot (1 open to new patients)
• Thalassemia (3 open to new patients)
• Thrombophilia (1 open to new patients)
• Thrombosis (1 open to new patients)
• Thrombotic Microangiopathies (1 open to new patients)
• Thyroid Cancer (2 open to new patients)
• Transcranial Magnetic Stimulation (2 open to new patients)
• Transitional Cell Carcinoma (1 open to new patients)
• Transplants (5 open to new patients)
• Treated With Radiation Therapy (1 open to new patients)
• TUBB4A-Related Leukodystrophy (1 open to new patients)
• Ulcerative Colitis (7 open to new patients)
• Unclassified Tumor, Malignant (1 open to new patients)
• Unresectable Malignant Solid Neoplasm (1 open to new patients)
• Urinary Bladder Tumor (1 open to new patients)
• Usher Syndrome (1 open to new patients)
• Van Der Knapp Disease (1 open to new patients)
• Vanishing White Matter Disease (1 open to new patients)
• Vascular Malformation (2 open to new patients)
• Vision Disorders (2 open to new patients)
• Vomiting (1 open to new patients)
• Von Willebrand Disease (1 open to new patients)
• Wheezing (1 open to new patients)
• Wheezing Lower Respiratory Illness (1 open to new patients)
• White Matter Disease (1 open to new patients)
• Wilms Tumor (3 open to new patients)
• Wolman Disease (1 open to new patients)
• X-Linked Intellectual Disability (1 open to new patients)
• X-Linked Protoporphyria (1 open to new patients)
• Zellweger Syndrome (1 open to new patients)