Clinical Trials Open to People Under 18
(237 trials open to new patients)

• AADC Deficiency (1 open to new patients)
• Abnormal Glucose Tolerance (1 open to new patients)
• Abortion (1 open to new patients)
• Activating RAS Mutation (1 open to new patients)
• Acute Lymphoblastic Leukemia (11 open to new patients)
• Acute Myeloid Leukemia (3 open to new patients)
• Acute Porphyria (1 open to new patients)
• Acute Promyelocytic Leukemia (1 open to new patients)
• ADA Deficiency (2 open to new patients)
• Adenovirus Infection (1 open to new patients)
• Adrenal Cortex Carcinoma (1 open to new patients)
• Aicardi Syndrome (1 open to new patients)
• ALK Fusion Protein Expression (1 open to new patients)
• ALK Gene Mutation (1 open to new patients)
• ALK Gene Translocation (1 open to new patients)
• Alpha Thalassemia (1 open to new patients)
• Alpha Thalassemia Major (2 open to new patients)
• Amino Acid Metabolism, Inborn Errors (1 open to new patients)
• Anal Cancer (1 open to new patients)
• ANCA-Associated Vasculitis (1 open to new patients)
• Anemia (10 open to new patients)
• Anesthesia (1 open to new patients)
• Anorexia (1 open to new patients)
• Anxiety Disorders (1 open to new patients)
• Aortic Stenosis (1 open to new patients)
• ARAF Gene Mutation (1 open to new patients)
• ASAH1 Mutation (1 open to new patients)
• Asthma (3 open to new patients)
• Astrocytoma (6 open to new patients)
• Atopic Dermatitis (Eczema) (1 open to new patients)
• Atypical Teratoid Rhabdoid Tumor (1 open to new patients)
• Autism (2 open to new patients)
• Autoimmune Disease (1 open to new patients)
• BCR-ABL1 Fusion Protein Expression (1 open to new patients)
• Beta Thalassemia (2 open to new patients)
• Bile Acid Synthesis Disorders (1 open to new patients)
• Birth Asphyxia (1 open to new patients)
• Birth Defect (1 open to new patients)
• Blood Pressure (2 open to new patients)
• Bone Cancer (1 open to new patients)
• Bone Marrow Transplant (4 open to new patients)
• BRAF Gene Mutation (2 open to new patients)
• BRAF NP_004324.2:p.V600X (1 open to new patients)
• Brain Death (1 open to new patients)
• Brain Diseases, Metabolic, Inborn (1 open to new patients)
• Brain Disorders (1 open to new patients)
• Brain Tumor (7 open to new patients)
• BRCA 1 Gene Mutation (1 open to new patients)
• BRCA 2 Gene Mutation (1 open to new patients)
• Breast Cancer (1 open to new patients)
• Breast Milk Substitute Intolerance (1 open to new patients)
• Breastfeeding (2 open to new patients)
• Cancer, General (5 open to new patients)
• Cardiac Anomalies (1 open to new patients)
• Cardiac Surgery (1 open to new patients)
• Cardiovascular Complication (1 open to new patients)
• Cardiovascular Disease (2 open to new patients)
• Cardiovascular Risk Factor (1 open to new patients)
• Cavernous Angioma, Familial (1 open to new patients)
• CD20 Positive (1 open to new patients)
• CD22 Positive (1 open to new patients)
• CDKL5 Disorder (1 open to new patients)
• Central Nervous System Anomalies (1 open to new patients)
• Central Nervous System Embryonal Tumor (1 open to new patients)
• Central Nervous System Neoplasm (13 open to new patients)
• Cerebral Cavernous Hemangioma (1 open to new patients)
• Cerebral Cavernous Malformations (1 open to new patients)
• Cerebral Palsy (1 open to new patients)
• Choriocarcinoma (1 open to new patients)
• Chronic Illness (1 open to new patients)
• Claudication (1 open to new patients)
• Claudication, Intermittent (1 open to new patients)
• Clostridium Difficile Infection (1 open to new patients)
• CNS Malignancies (1 open to new patients)
• CNS Tumor (1 open to new patients)
• Coccidioidomycosis (1 open to new patients)
• Cognition (1 open to new patients)
• Colon Cancer (1 open to new patients)
• Colorectal Cancer (2 open to new patients)
• Complex Congenital Heart Defect (1 open to new patients)
• Congenital Heart Defects (1 open to new patients)
• Congenital Mesoblastic Nephroma (2 open to new patients)
• Contraception (1 open to new patients)
• Crohn's Disease (3 open to new patients)
• Cutaneous Porphyrias (1 open to new patients)
• Cystic Fibrosis (2 open to new patients)
• Cytomegalovirus Infections (1 open to new patients)
• Cytopenia (1 open to new patients)
• Deleterious ATM Gene Mutation (1 open to new patients)
• Deleterious RAD51C Gene Mutation (1 open to new patients)
• Deleterious RAD51D Gene Mutation (1 open to new patients)
• Dental Plaque (1 open to new patients)
• Depression (1 open to new patients)
• Desmoid-Type Fibromatosis (1 open to new patients)
• Developmental Defect (1 open to new patients)
• Developmental Delay (1 open to new patients)
• Diabetes (5 open to new patients)
• Diabetes Type 1 (5 open to new patients)
• Dislocations (1 open to new patients)
• Dislocation of Shoulder Region (1 open to new patients)
• Disorders of the Immune System (1 open to new patients)
• Down Syndrome (1 open to new patients)
• Drug Use (1 open to new patients)
• Duchenne Muscular Dystrophy (1 open to new patients)
• Dysplasia (1 open to new patients)
• Eating Disorder (1 open to new patients)
• EBV Infection (1 open to new patients)
• Elevated Alpha-Fetoprotein (1 open to new patients)
• Encephalopathy (1 open to new patients)
• Environmental Exposure (1 open to new patients)
• Ependymal Tumor (1 open to new patients)
• Ependymoma (10 open to new patients)
• Epilepsy (1 open to new patients)
• Epstein Barr Virus (1 open to new patients)
• Ewing Sarcoma (11 open to new patients)
• Exostoses, Multiple Hereditary (1 open to new patients)
• Extragonadal Embryonal Carcinoma (1 open to new patients)
• EZH2 Gain of Function (1 open to new patients)
• EZH2 Gene Mutation (1 open to new patients)
• Farber Disease (1 open to new patients)
• Farber Lipogranulomatosis (1 open to new patients)
• Feeding, Bottle (1 open to new patients)
• Fetal Hydrops (2 open to new patients)
• FGFR1 Gene Mutation (1 open to new patients)
• FGFR2 Gene Mutation (1 open to new patients)
• FGFR3 Gene Mutation (1 open to new patients)
• FGFR4 Gene Mutation (1 open to new patients)
• Fibrosing Colonopathy (1 open to new patients)
• Fibrosis (2 open to new patients)
• FOXG1 Syndrome (1 open to new patients)
• Ganglioneuroblastoma (3 open to new patients)
• Gastrointestinal Anomalies (1 open to new patients)
• Genetic Diseases, Inborn (1 open to new patients)
• Genetic Diseases, X-Linked (1 open to new patients)
• Genetic Inborn Errors of Metabolism (4 open to new patients)
• Genito-urinary Anomalies (1 open to new patients)
• Germ Cell Tumor (10 open to new patients)
• Giant Cell Arteritis (1 open to new patients)
• Glioblastoma (5 open to new patients)
• Glioma (22 open to new patients)
• GNA11 Gene Mutation (2 open to new patients)
• GNAQ Gene Mutation (2 open to new patients)
• Graft Versus Host Disease (3 open to new patients)
• Granulomatosis with Polyangiitis (2 open to new patients)
• Granulomatous Disease (1 open to new patients)
• Growth Delay (1 open to new patients)
• Gulf War Syndrome (1 open to new patients)
• Health-Related Quality of Life (1 open to new patients)
• Heart Failure (1 open to new patients)
• Hematologic Malignancies (5 open to new patients)
• Hematological Malignancy (1 open to new patients)
• Hematopoietic Cell Transplantation (8 open to new patients)
• Hemispheric (1 open to new patients)
• Hemoglobinopathy (5 open to new patients)
• Hepatitis B (1 open to new patients)
• Hepatitis C (4 open to new patients)
• Hepatoblastoma (11 open to new patients)
• Hepatocellular Carcinoma (2 open to new patients)
• Hereditary Hemorrhagic Telangiectasia (1 open to new patients)
• Hidradenitis Suppurativa (1 open to new patients)
• -High Blood Pressure (8 open to new patients)
• Hispanic Americans (1 open to new patients)
• Histiocytic and Dendritic Cell Neoplasm (1 open to new patients)
• Histiocytic Disorders (1 open to new patients)
• Histiocytosis (6 open to new patients)
• HIV/AIDS (3 open to new patients)
• Hodgkin's Lymphoma (4 open to new patients)
• HRAS Gene Mutation (2 open to new patients)
• Huntington's Disease (1 open to new patients)
• Hyperparathyroidism, Primary (1 open to new patients)
• Hypophosphatemic Rickets (1 open to new patients)
• Hypoplastic Left Heart Syndrome (1 open to new patients)
• IDH1 Gene Mutation (1 open to new patients)
• IDH2 Gene Mutation (1 open to new patients)
• Immune Deficiency (1 open to new patients)
• Immunodeficiencies (3 open to new patients)
• Immunotherapy (2 open to new patients)
• Indeterminate Colitis (1 open to new patients)
• Ineffective Erythropoiesis (1 open to new patients)
• Infection (1 open to new patients)
• Infertility (1 open to new patients)
• Inflammatory Bowel Disease (6 open to new patients)
• Influenza (1 open to new patients)
• Inherited Abnormalities of Platelets (1 open to new patients)
• Inherited Disorders of Metabolism (1 open to new patients)
• Insomnia (1 open to new patients)
• Instability, Shoulder (1 open to new patients)
• Intellectual Disability (1 open to new patients)
• Invasive Candidiasis (1 open to new patients)
• Irritable Bowel Syndrome (1 open to new patients)
• Juvenile Xanthogranuloma (1 open to new patients)
• Kidney Cancer (2 open to new patients)
• Kidney Disease (3 open to new patients)
• Kidney Transplant (2 open to new patients)
• KRAS Gene Mutation (2 open to new patients)
• Langerhans Cell Histiocytosis (11 open to new patients)
• Leaky SCID (2 open to new patients)
• Lennox-Gastaut Syndrome (1 open to new patients)
• Leukemia (17 open to new patients)
• Liver Cancer (2 open to new patients)
• Liver Disease (2 open to new patients)
• Liver Transplant (2 open to new patients)
• Loss of BRG1 Protein Expression (1 open to new patients)
• Loss of INI 1 Protein Expression (1 open to new patients)
• Lower Respiratory Tract Infections (1 open to new patients)
• Lung Cancer (1 open to new patients)
• Lymphadenopathy (1 open to new patients)
• Lymphoma (19 open to new patients)
• Lymphoproliferative Disorder (1 open to new patients)
• Malignant Central Nervous System Neoplasm (2 open to new patients)
• Malignant Neoplasm (5 open to new patients)
• Malignant Solid Neoplasm (17 open to new patients)
• MAP2K1 Gene Mutation (1 open to new patients)
• MAPK1 Gene Mutation (1 open to new patients)
• Matched Targeted Therapy (1 open to new patients)
• MECP2 Duplication Syndrome (1 open to new patients)
• Medulloblastoma (12 open to new patients)
• Melanoma (1 open to new patients)
• Metabolic Disease (1 open to new patients)
• Microbial Colonization (1 open to new patients)
• Microscopic Polyangiitis (1 open to new patients)
• Migraine (3 open to new patients)
• Minimal Residual Disease (1 open to new patients)
• MITF Positive (1 open to new patients)
• Monosomy 7 (1 open to new patients)
• MPS II (1 open to new patients)
• Mucopolysaccharidosis (4 open to new patients)
• Multiple Anomalies (1 open to new patients)
• Multiple Congenital Anomaly (1 open to new patients)
• Multiple Myeloma (2 open to new patients)
• Muscular Diseases (1 open to new patients)
• Muscular Disorders, Atrophic (1 open to new patients)
• Muscular Dystrophies (1 open to new patients)
• Musculoskeletal Disease (1 open to new patients)
• Myelodysplastic Syndrome (1 open to new patients)
• Myeloproliferative Neoplasms (2 open to new patients)
• N-Laurylsphingosine Deacylase Deficiency (1 open to new patients)
• Narcotic Addiction (1 open to new patients)
• Neonatal Abstinence Syndrome (1 open to new patients)
• Neonatal Encephalopathy (1 open to new patients)
• Nervous System Diseases (1 open to new patients)
• Neuroblastoma (24 open to new patients)
• Neurodegenerative Disease (1 open to new patients)
• Neurofibromatosis Type 1 (3 open to new patients)
• Neuromuscular Diseases (1 open to new patients)
• Newborn (1 open to new patients)
• NF1 Gene Mutation (3 open to new patients)
• NMYC Gene Amplification (1 open to new patients)
• Non Hodgkin Lymphoma (14 open to new patients)
• Non-Small Cell Lung Cancer (1 open to new patients)
• Nonmalignant Diseases (4 open to new patients)
• NRAS Gene Mutation (2 open to new patients)
• NTRK1 Fusion Positive (1 open to new patients)
• NTRK2 Fusion Positive (1 open to new patients)
• NTRK3 Fusion Positive (1 open to new patients)
• Obesity (4 open to new patients)
• Omenn Syndrome (2 open to new patients)
• Organ Donation (1 open to new patients)
• Organ Transplant Failure or Rejection (1 open to new patients)
• Osteoarthritis (1 open to new patients)
• Osteoid Osteoma (1 open to new patients)
• Osteosarcoma (13 open to new patients)
• Ovarian Embryonal Carcinoma (1 open to new patients)
• Ovarian Tumor (1 open to new patients)
• Pain (1 open to new patients)
• Pain Crisis (1 open to new patients)
• Pancreatitis (2 open to new patients)
• Patients Transplanted With NiCord/CordIn (1 open to new patients)
• Pediatric Cancer (1 open to new patients)
• Pediatric Central Nervous System Tumor (1 open to new patients)
• Peripheral Arterial Disease (1 open to new patients)
• Peripheral Primitive Neuroectodermal Tumor (6 open to new patients)
• Philadelphia Chromosome Positive (1 open to new patients)
• Physical Activity (1 open to new patients)
• Plexiform Neurofibroma (1 open to new patients)
• Pneumonia (1 open to new patients)
• Polyarteritis Nodosa (1 open to new patients)
• Polycystic Ovary Syndrome (1 open to new patients)
• Post-Traumatic Stress Disorders (1 open to new patients)
• Pregnancy (1 open to new patients)
• Premature Birth of Newborn (1 open to new patients)
• Preterm Infant (1 open to new patients)
• PTPN11 Gene Mutation (1 open to new patients)
• Pulmonary Arterial Hypertension (3 open to new patients)
• RB1 Positive (1 open to new patients)
• Recurrent Tumor (1 open to new patients)
• Refractory Central Nervous System Neoplasm (12 open to new patients)
• Refractory Central Nervous System Tumor (1 open to new patients)
• Refractory Hepatoblastoma (4 open to new patients)
• Refractory Langerhans Cell Histiocytosis (8 open to new patients)
• Refractory Malignant Solid Neoplasm (15 open to new patients)
• Refractory Neurofibromatosis Type 1 (1 open to new patients)
• Refractory Osteosarcoma (8 open to new patients)
• Refractory Tumor (1 open to new patients)
• Relapsed Central Nervous System Tumor (1 open to new patients)
• Renal Cell Carcinoma (1 open to new patients)
• Reproductive Health (1 open to new patients)
• Reticular Dysgenesis (2 open to new patients)
• Retinitis Pigmentosa (1 open to new patients)
• Rett Syndrome (1 open to new patients)
• Rhabdoid Tumor (11 open to new patients)
• Rhabdomyosarcoma (13 open to new patients)
• Rheumatic Joint Disease (1 open to new patients)
• Risk Reduction (1 open to new patients)
• ROS1 Fusion Positive (1 open to new patients)
• ROS1 Gene Mutation (1 open to new patients)
• ROS1 Gene Translocation (1 open to new patients)
• Sanfilippo Syndrome (1 open to new patients)
• Sarcoma (14 open to new patients)
• Seminoma (1 open to new patients)
• Severe Combined Immunodeficiency (4 open to new patients)
• Sexually Transmitted Infections (1 open to new patients)
• Short Bowel Syndrome (1 open to new patients)
• Sickle Cell Anemia (9 open to new patients)
• Sickle Cell Disorders (1 open to new patients)
• Skeletal Anomalies (1 open to new patients)
• Skin Cancer/Melanoma (1 open to new patients)
• Sleep Disorders (1 open to new patients)
• SMARCA4 Gene Inactivation (1 open to new patients)
• SMARCB1 Gene Inactivation (1 open to new patients)
• SMARCB1 Gene Mutation (1 open to new patients)
• Soft Tissue Sarcoma (11 open to new patients)
• Solid Neoplasm (3 open to new patients)
• Solid Organ Transplantation Recipient (1 open to new patients)
• Solid Tumor (22 open to new patients)
• Spinal Column Tumor (1 open to new patients)
• Spinal Cord Injuries (1 open to new patients)
• Spinocerebellar Ataxia (1 open to new patients)
• Splenomegaly (1 open to new patients)
• Squamous Cell Carcinoma (1 open to new patients)
• Stromal Neoplasm (1 open to new patients)
• Structural Anomalies (1 open to new patients)
• Subluxations (1 open to new patients)
• Substance Abuse (1 open to new patients)
• Sudden Cardiac Death (1 open to new patients)
• Supraventricular Tachycardia (2 open to new patients)
• T Cell Lymphoma (1 open to new patients)
• Tachycardia, Atrioventricular Nodal Reentry (1 open to new patients)
• Tachycardia, Paroxysmal (1 open to new patients)
• Tachycardia, Reciprocating (1 open to new patients)
• Takayasu's Arteritis (1 open to new patients)
• Teratoma (2 open to new patients)
• Testicular Cancer (1 open to new patients)
• Testicular Tumor (1 open to new patients)
• Thalassemia (4 open to new patients)
• Thorax Anomalies (1 open to new patients)
• Thrombotic Microangiopathies (1 open to new patients)
• Thyroid Cancer (1 open to new patients)
• Thyroid Gland Medullary Carcinoma (1 open to new patients)
• Tracheostomy Infection (1 open to new patients)
• Transplant (1 open to new patients)
• Transplantation Disease Transmission (1 open to new patients)
• Traumatic Brain Injury (1 open to new patients)
• Treatment-Related Cancer (1 open to new patients)
• Trisomy 21 (1 open to new patients)
• Trisomy 21 Mosaicism (1 open to new patients)
• TSC1 Gene Mutation (1 open to new patients)
• TSC2 Gene Mutation (1 open to new patients)
• Undesired Pregnancy (1 open to new patients)
• Unintended Pregnancy (1 open to new patients)
• Urea Cycle Disorders (1 open to new patients)
• Vascular Calcification (1 open to new patients)
• Vascular Disease (2 open to new patients)
• Vascular Occlusion (1 open to new patients)
• Vaso-occlusive Crisis (2 open to new patients)
• Veno-occlusive Disease (1 open to new patients)
• Venous Thromboembolism (1 open to new patients)
• Wheezing (1 open to new patients)
• Wilms Tumor (11 open to new patients)
• X-linked Hypophosphatemia (1 open to new patients)
• X-Linked Severe Combined Immunodeficiency (3 open to new patients)
• β-thalassemia (1 open to new patients)