Dystonia clinical trials at UCSF
2 in progress, 1 open to eligible people
Dystonia is a condition that causes muscles to contract involuntarily, leading to repetitive movements or abnormal posture. UCSF is recruiting participants for a clinical trial on Deep Brain Stimulation (DBS) to study its outcomes. Another DBS trial is already happening, but not currently seeking new participants.
open to all eligible people
The primary objective of this study is to characterize real-world clinical outcomes of Deep Brain Stimulation (DBS) using retrospective review of de-identified patient records.
San Francisco, California and other locations
Sorry, in progress, not accepting new patients
This is an exploratory pilot study to identify neural correlates of specific motor signs in Parkinson's disease (PD) and dystonia, using a novel totally implanted neural interface that senses brain activity as well as delivering therapeutic stimulation. Parkinson's disease and isolated dystonia patients will be implanted unilaterally or bilaterally with a totally internalized bidirectional neural interface, Medtronic Summit RC+S. This study includes three populations: ten PD patients undergoing deep brain stimulation in the subthalamic nucleus (STN), ten PD patients with a globus pallidus (GPi) target and five dystonia patients. All groups will test a variety of strategies for feedback-controlled deep brain stimulation, and all patients will undergo a blinded, small pilot clinical trial of closed-loop stimulation for thirty days.
San Francisco, California
Our lead scientists for Dystonia research studies include Philip Starr.