Preeclampsia clinical trials at UCSF

4 in progress, 1 open to eligible people

Showing trials for

  • Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

    open to eligible females ages 14-35

    The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there are multiple factors associated with adherence with aspirin therapy that will be important to identify to enable optimal implementation of study findings and population-level benefits.

    San Francisco, California and other locations

  • Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

    Sorry, in progress, not accepting new patients

    A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.

    San Francisco, California and other locations

  • Gestational Hypertension and Preeclampsia Blood Pressure (BP) Treatment Goals Less Than 140/90 vs. Less Than 160/110 mmHg: The GOALPOST Trial

    Sorry, not yet accepting patients

    This is a phase-III multi-center open-label randomized clinical trial of 4,120 individuals between 23 weeks, 0 days and 35 weeks, 6 days gestation with gestational hypertension or preeclampsia without severe features randomized to antihypertensive medication to a target blood pressure (BP) of <140/90 mmHg or to no treatment for non-severe hypertension < 160/110 mmHg (usual care). The primary endpoint is an adverse pregnancy composite comprised of preeclampsia with end-organ damage, medically indicated preterm delivery <37 weeks 0 days gestation, fetal/neonatal/infant death, or placental abruption.

    San Francisco, California and other locations

  • Natural Versus Programmed Frozen Embryo Transfer (NatPro)

    Sorry, in progress, not accepting new patients

    NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent).

    San Francisco, California and other locations

Our lead scientists for Preeclampsia research studies include .

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