Preeclampsia clinical trials at UCSF
3 in progress, 2 open to eligible people
Preeclampsia is when pregnant individuals experience high blood pressure and possible organ damage. UCSF is evaluating CPAP treatment for sleep apnea in pregnant individuals. They are also studying the effectiveness of two aspirin doses in preventing pregnancy-related hypertension.
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy
open to eligible females ages 18 years and up
A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.
San Francisco, California and other locations
Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
open to eligible females ages 14-35
The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there are multiple factors associated with adherence with aspirin therapy that will be important to identify to enable optimal implementation of study findings and population-level benefits.
San Francisco, California and other locations
Natural Versus Programmed Frozen Embryo Transfer (NatPro)
Sorry, in progress, not accepting new patients
NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent).
San Francisco, California and other locations
Our lead scientists for Preeclampsia research studies include Mary Norton, MD.
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