Fractured Spine clinical trials at UCSF

2 in progress, 1 open to eligible people

A fractured spine means a break in one or more bones in the back. UCSF is studying how blood flow and certain markers can help people with spine injuries. This study involves patients with recent neck or upper back injuries.

Showing trials for

  • Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

    open to eligible people ages 17 years and up

    This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury. The lumbar intrathecal catheter will be inserted pre-operatively for the measurement of ITP and the collection of cerebrospinal fluid (CSF) samples. SCPP will be calculated as the difference between MAP and the ITP. There are two important distinct yet related objectives in this prospective interventional study. 1. Determine the effect of SCPP maintenance ≥ 65 mmHg in acute SCI on neurologic recovery as measured by ASIA Impairment Scale (AIS) grade conversion and motor score improvement. 2. Collect CSF and blood samples for the measurement of neurochemical biomarkers and storage for future biomarker discovery and validation studies.

    San Francisco, California and other locations

  • Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study

    Sorry, not currently recruiting here

    A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.

    San Francisco, California and other locations

Our lead scientists for Fractured Spine research studies include .

Last updated: