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Migraine clinical trials at UCSF
4 in progress, 2 open to new patients

  • CHOCOlate MeLatonin for AdolescenT MigrainE

    open to eligible people ages 3-17

    Existing treatments for acute migraine are not effective for all children and adolescents, and can cause side effects. We propose a dose-finding study of melatonin for acute migraine treatment in children and adolescents to determine the best dose to bring forward in a future fully-powered efficacy trial.

    San Francisco, California

  • Melatonin for Adolescent Migraine Prevention Study

    open to eligible people ages 10-17

    This will be a randomized, multi-site double-blind placebo-controlled trial of melatonin (2 different dosing arms) vs. placebo for migraine prevention in adolescents. We intend to enroll approximately 210 participants over 15 months at two sites: UCLA and UCSF. The duration of participation for each participant will be 4 months.

    San Francisco, California and other locations

  • Sphenopalatine Ganglion Blocks RCT

    Sorry, not yet accepting patients

    RCT of Sphenopalatine Ganglion (SPG) Blocks using anesthetics vs. placebo for migraine.

    San Francisco, California

  • Study of Pediatric Migraine: The Pediatric Migraine Registry

    Sorry, not yet accepting patients

    This is a multi-center registry that will prospectively collect regulatory compliant data from children and adolescents with migraine. This study will enroll approximately 200 participants from approximately 20 sites and will examine migraine symptoms, therapeutics used, and biomarkers associated with migraine.

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