Spinal Paralysis clinical trials at UCSF

1 research study open to eligible people

Spinal paralysis is when you cannot move parts of your body because of spinal cord injury. UCSF is recruiting patients for studies on new treatments for spinal cord injuries. One study involves monitoring pressure and biomarkers in patients with severe spinal cord injuries.

Showing trials for

  • Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

    open to eligible people ages 17 years and up

    This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury. The lumbar intrathecal catheter will be inserted pre-operatively for the measurement of ITP and the collection of cerebrospinal fluid (CSF) samples. SCPP will be calculated as the difference between MAP and the ITP. There are two important distinct yet related objectives in this prospective interventional study. 1. Determine the effect of SCPP maintenance ≥ 65 mmHg in acute SCI on neurologic recovery as measured by ASIA Impairment Scale (AIS) grade conversion and motor score improvement. 2. Collect CSF and blood samples for the measurement of neurochemical biomarkers and storage for future biomarker discovery and validation studies.

    San Francisco, California and other locations

Our lead scientists for Spinal Paralysis research studies include .

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