Meditation clinical trials at UCSF
5 in progress, 2 open to eligible people
Digital Interventions on Cognition, Wellbeing, Stress, and Sleep in Older Adults
open to eligible people ages 60-85
The goal of this proposed research is to collect pilot data to test the hypothesis that treatment with a novel form of closed-loop digital meditation (MediTrain) will lead to a greater magnitude of gains in cognitive abilities in patients with mild cognitive impairment (MCI), compared to OA without cognitive impairment, and will lead to improvements in quantitative measures of sleep.
San Francisco, California
Enhancing Attention and Wellbeing Using Digital Therapeutics
open to eligible people ages 60-99
The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascular risk, and race/ethnicity). This knowledge gained from his high-impact study with transform the field of cognitive interventions, paving the way for a precision medicine model for cognitive enhancing interventions that improve quality of life for older adults and individuals with cognitive deficits at risk of developing dementia.
San Francisco, California
Accelerating Cognitive Gains From Digital Inverventions With Noninvasive Brain Stimulation
Sorry, in progress, not accepting new patients
The overall goal of this project is to collect pilot feasibility and early efficacy data showing improvements in cognition and wellbeing in adults with mild cognitive impairment (MCI) through a combination treatment of non-invasive brain stimulation (transcranial alternating current stimulation (tACS)) and a one of two digital cognitive interventions.
San Francisco, California
Dynamic Neural Systems Underlying Social-emotional Functions in Older Adults
Sorry, in progress, not accepting new patients
Assess the impact of a remote, app-delivered digital meditation intervention on emotional well-being of lonely older adults. Neuroimaging, electrophysiological (EEG), and autonomic physiology will be used to assess the neural correlates of the intervention. EEG and autonomic physiology will be collected while participants watch 30 min of an awe-inspiring movie. fMRI and autonomic physiology will be collected in the context of a social exploration/exploitation task.
San Francisco, California
Mindful Motivation for Reducing Binge Eating
Sorry, in progress, not accepting new patients
The aim of this study is to test how acceptable and feasible a new eating intervention is in people with overweight and binge eating. This intervention combines mindful eating with motivational interviewing to target binge eating. The main questions this clinical trial aims to answer are: How well do participants accept the new intervention (acceptability)? Is the intervention practical and easy to implement (feasibility)? In this trial researchers will compare the new eating intervention (motivational interviewing for mindful eating + digital meditation) to an active control (digital meditation) to see if the intervention can help reduce binge eating. Participants will: 1. Take online questionnaires at four different time points 2. Provide body composition and samples to measure glucose levels 3. Meditate for at least 10 minutes a day 4. If assigned to the Mindful Motivation group, 8 weeks of brief counseling
San Francisco, California
Our lead scientists for Meditation research studies include Christine Walsh, PhD David A Ziegler, PhD Elissa Epel, PhD Rachel Radin, PhD Lorenzo Pasquini, PhD Adam Gazzaley, MD/PhD.
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