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Scoliosis clinical trials at UCSF

5 in progress, 4 open to eligible people

Scoliosis is a condition where the spine curves to the side. UCSF is investigating various surgical methods for complicated spine deformities in adults. Another trial focuses on whether placebos can help manage pain in teens undergoing scoliosis surgery. The studies compare results to develop better ways to treat scoliosis.

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  • Placebo (COLP) for Pain in Adolescent Idiopathic Scoliosis (AIS) Surgery+Surgical Treatment of Idiopathic Scoliosis

    open to eligible people ages 10-18

    This study aims to investigate the effects of conditioning with open-label placebos on standard postoperative treatment for patients undergoing surgery for idiopathic scoliosis in a randomized controlled, 6-week trial with 64 AIS patients randomly assigned to one of two arms: Open-label Placebo (COLP) + treatment as usual TAU / TAU control. The study involves collecting data from your child's medical record. At each regular clinic visit, the patient clinical data will be collected by the research coordinator. Surveys will be collected including:• PROMIS for the age group 10 to 18 years.

    San Francisco, California

  • Complex Adult Deformity Surgery (CADS)

    open to eligible people ages 18 years and up

    Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

    San Francisco, California and other locations

  • Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

    open to eligible people ages 18 years and up

    Evaluate surgical treatment outcomes and identify best practice guidelines for complex adult spinal deformity (ASD) patients treated with minimally invasive approach, including radiographic and clinical outcomes, surgical and postoperative complications, risk factors for and revision surgery rates, and the role of standard work to improve patient outcomes and reduce surgical and postoperative complications.

    San Francisco, California and other locations

  • Radiographic and Clinical Evaluation of Surgical Treatment for Cervical Deformity: A Multi-Center Study 2.0

    open to eligible people ages 18 years and up

    Multi-center, prospective, non-randomized study to evaluate outcomes of surgically treated patients with adult cervical spinal deformity.

    San Francisco, California and other locations

  • Adult Spinal Deformity Outcomes Database Registry

    Sorry, in progress, not accepting new patients

    The clinical, radiographic, and HRQL outcomes will be compared in operative and nonoperative adult spinal deformity patients.

    San Francisco, California and other locations

Our lead scientists for Scoliosis research studies include .

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