CADASIL clinical trials at UCSF
2 research studies open to eligible people
CADASIL is a genetic disorder that affects blood vessels in the brain. UCSF is studying CADASIL to learn more about its risk factors and how it progresses over time. UCSF also collects data and samples from patients with myelin disorders to support research.
Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study
open to eligible people ages 18 years and up
This is an observational study to better understand the risk factors and progression of CADASIL, a leading cause of vascular cognitive impairment and dementia (VCID). 575 participants will be enrolled and can expect to be on study for up to 5 years.
San Francisco, California and other locations
Myelin Disorders Biorepository Project
open to all eligible people
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies, develop biomarkers for use in future clinical trials, and better understand the natural history of these disorders. The knowledge gained from these efforts may help improve the diagnostic tools and treatment options available to patients in the future.
San Francisco, California and other locations
Our lead scientists for CADASIL research studies include Michael D Geschwind, MD.
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