Pregnancy clinical trials at UCSF
9 in progress, 4 open to eligible people
Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
open to eligible females ages 14-35
The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there…
San Francisco, California and other locations
Engaging Mothers & Babies; Reimagining Antenatal Care for Everyone (EMBRACE) Study
open to eligible females
This is a randomized comparative effectiveness study of two forms of enhanced prenatal care among 657 Medi-Cal eligible pregnant individuals in Fresno, California. The goal is to see whether group prenatal care with wrap around services versus…
San Francisco, California and other locations
Periviable GOALS Decision Support Tool
open to eligible people ages 18 years and up
The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery…
San Francisco, California and other locations
Commercial or Open Source Closed Loop Impact on Pregnancy Study
open to eligible females ages 18 years and up
The goal of this observational study is to better understand what happens when pregnant people with type 1 diabetes (T1D) use automated insulin delivery (AID) systems. The main questions this study aims to answer are: - What are the maternal and…
San Francisco, California
B Cell Levels In Infants Potentially Exposed To Ocrelizumab During Pregnancy
Sorry, in progress, not accepting new patients
This study will evaluate the potential placental transfer of ocrelizumab in women with clinically isolated syndrome (CIS) or multiple sclerosis (MS) [in line with the locally approved indications] whose last dose of ocrelizumab was administered any…
San Francisco, California and other locations
DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes
Sorry, not currently recruiting here
This is a non-inferiority patient-centered and pragmatic comparative-effectiveness pregnancy randomized controlled trial (RCT) with postpartum maternal and child follow-up through 2 years of 1,572 individuals with gestational diabetes mellitus (GDM) …
San Francisco, California and other locations
Natural Versus Programmed Frozen Embryo Transfer (NatPro)
Sorry, in progress, not accepting new patients
NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum…
San Francisco, California and other locations
Rigorous Evaluation of Yes and Know, a Fully Virtual Sexual Health and Well-Being Intervention for Youth
Sorry, not yet accepting patients
This study is a 2-arm cluster randomized controlled trial with approximately 1,200 youth aged 14-19 years to assess the effectiveness of Yes and Know, a sexual health education program. To be eligible, participants must be 14-19 years old and…
Pregnancy In the CoRonavirus (COVID-19) pandEmic
Sorry, in progress, not accepting new patients
Prospective nationwide cohort study of pregnant women enrolled early in gestation and followed for Covid-19 exposure and infection, with follow up of obstetrical outcomes and infant development through the first year of life.
San Francisco, California
Our lead scientists for Pregnancy research studies include Mary Norton, MD Heather Huddleston, MD Nasim Sobhani, MD Miriam Kuppermann, PhD, MPH.
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