Kidney Medullary Carcinoma clinical trials at UCSF
2 research studies open to eligible people
Kidney medullary carcinoma is a type of cancer that affects the kidney. UCSF is recruiting for clinical trials aimed at studying this condition. One trial involves collecting tissue, blood, and urine samples from younger patients to learn more about their tumors. Another trial is studying the effectiveness of tiragolumab and atezolizumab in treating relapsed or refractory tumors in children and adults with a specific gene mutation.
Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors
open to eligible people ages 12 months and up
This phase I/II trial studies how well tiragolumab and atezolizumab works when given to children and adults with SMARCB1 or SMARCA4 deficient tumors that that has either come back (relapsed) or does not respond to therapy (refractory). SMARCB1 or SMARCA4 deficiency means that tumor cells are missing the SMARCB1 and SMARCA4 genes, seen with some aggressive cancers that are typically hard to treat. Immunotherapy with monoclonal antibodies, such as tiragolumab and atezolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
San Francisco, California and other locations
open to eligible people ages up to 29 years
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Oakland, California and other locations