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Neurodegenerative Disease clinical trials at UCSF

2 in progress, 1 open to eligible people

Neurodegenerative diseases are conditions where the brain and nerves slowly stop working. UCSF is studying a new treatment called AMX0035 for Progressive Supranuclear Palsy. This trial will check if the treatment is safe and effective.

Showing trials for
  • AMX0035 and Progressive Supranuclear Palsy

    open to eligible people ages 40-80

    A35-009 (ORION) is a Phase 2b/3 trial to evaluate the efficacy and safety of AMX0035 in participants with Progressive Supranuclear Palsy (PSP), consisting of randomized, double blind placebo controlled phases, followed by an optional open-label extension phase.

    San Francisco, California and other locations

  • Brain Health Registry: An Online Registry to Identify and Assess Subjects for Brain Research

    Sorry, accepting new patients by invitation only

    The overall goal of this project is to identify, assess and longitudinally monitor subjects who are interested in participating in brain research. Participants will enroll through the website, BrainHealthRegistry.org, and provide informed consent prior to any study activities. The website will collect a variety of information, including participants' overall health, memory complaints, family history of dementia and Alzheimer's disease (AD), mood status, sleep, diet, and exercise-all through self-reported online questionnaires. Participants will also be ask to take online cognitive tests, and to return to the website at regular intervals, to complete follow-up questionnaires and neuropsychological assessments. Everyone over the age of 18 is welcome to participate. To join the Brain Health Registry, please visit www.BrainHealthRegistry.org.

    San Francisco, California

Our lead scientists for Neurodegenerative Disease research studies include .

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