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Eclampsia clinical trials at UCSF

4 in progress, 2 open to eligible people

Eclampsia is a serious condition during pregnancy that causes seizures. UCSF is studying if using CPAP for sleep apnea can help pregnant women with this condition. Another study is looking at different methods of frozen embryo transfer.

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  • Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

    open to eligible females ages 18 years and up

    A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.

    San Francisco, California and other locations

  • Natural Versus Programmed Frozen Embryo Transfer (NatPro)

    open to eligible females ages 18-41

    NatPro is a two-arm, parallel-group, multi-center, randomized trial in which women undergoing frozen embryo transfer (FET) will be randomized to receive either a modified natural cycle (corpus luteum present) or a programmed cycle (corpus luteum absent).

    San Francisco, California and other locations

  • Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

    Sorry, not yet accepting patients

    The overall goal of this large, pragmatic, comparative effectiveness trial is to test the hypothesis that among at-risk individuals, 162 mg/day aspirin is superior to 81 mg/day in preventing Hypertensive disorders of pregnancy (HDP), and that there are multiple factors associated with adherence with aspirin therapy that will be important to identify to enable optimal implementation of study findings and population-level benefits.

    San Francisco, California and other locations

  • Expanded NIPT for Pregnancy Complications

    Sorry, in progress, not accepting new patients

    This study evaluates the utility of expanded panel non-invasive prenatal testing (NIPT) in detecting confined placental mosaicism of rare autosomal trisomies among pregnancies with placentally-mediated complications, including fetal growth restriction and severe preeclampsia.

    San Francisco, California

Our lead scientists for Eclampsia research studies include .

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