Primary Hyperparathyroidism clinical trials at UCSF

3 in progress, 2 open to eligible people

Primary hyperparathyroidism is a condition where the parathyroid glands produce too much hormone. UCSF is conducting studies on a PET scan using 18F-fluorocholine and a special light tool for surgery. These trials might help doctors better find and treat the affected glands.

Showing trials for

  • 18F-Fluorocholine Positron Emission Tomography (PET) for the Detection of Parathyroid Adenomas

    open to eligible people ages 13 years and up

    This is a prospective single arm single center Phase III study evaluating the ability of 18F-fluorocholine to detect the location of parathyroid adenomas.

    San Francisco, California

  • Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During Parathyroidectomy

    open to eligible people ages 18 years and up

    The goal of this study is to assess whether using PTeye (AiBiomed, Santa Barbara, CA) - a NIRAF detection modality - can improve patient outcomes and reduce healthcare associated costs after parathyroid surgeries. By being able to quickly and definitively locate parathyroid glands while in the operating room, the duration of surgical procedure could be further reduced. In addition, the number of frozen section biopsy and associated costs can be minimized. Furthermore, repeat surgeries as a result of missing a diseased parathyroid gland at the time of the initial parathyroidectomy for hyperparathyroidism could potentially be avoided.

    San Francisco, California

  • Parathyroid Tumor Clonal Status

    Sorry, in progress, not accepting new patients

    To define the frequency of monoclonal-X and polyclonal-X tumors in PHPT participants having parathyroidectomy (PTX) and to define the relationship between parathyroid tumor clonal status and multiple gland neoplasia (MGN), we will compare surgical and pathologic outcomes to tumor clonal status in a multicenter cohort of patients having bilateral neck exploration (BNE) and PTX (primary objectives).

    San Francisco, California and other locations

Our lead scientists for Primary Hyperparathyroidism research studies include .

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