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Pancreatitis clinical trials at UCSF
4 in progress, 2 open to new patients

  • A Prospective Observational Study of TPIAT

    open to all eligible people

    Multi-center, prospective, observational cohort study of patients undergoing total pancreatectomy with islet autotransplantation (TPIAT)

    San Francisco, California and other locations

  • Pediatric Longitudinal Cohort Study of Chronic Pancreatitis

    open to eligible people ages up to 17 years

    The investigators will enroll a total of 860 patients under 18 years of age with ARP or CP. Included in the total are the 502 patients in the INSPPIRE 1 database who are planned to be reenrolled under this protocol over the next 4 years. Patient questionnaires and physician surveys will be applied at the time of enrollment and annually thereafter as long as possible. At the first study visit after turning 18 years of age, the patient will sign the informed consent to continue in the study. Specifically, the investigators will define the demographics of the pediatric ARP and CP cohort, describe risk factors, presence of family history of acute and chronic pancreatitis, diabetes and pancreatic cancer and assess disease burden and sequelae.

    San Francisco, California and other locations

  • A Randomized Controlled Trial of IV Ketorolac to Prevent Post-ERCP Pancreatitis

    Sorry, not yet accepting patients

    Determine if IV ketorolac is an effective agent in the prevention of post-ERCP pancreatitis. Determine if IV ketorolac provides improved post-procedure analgesia. Determine if systemic mediators of inflammation are reduced in patients receiving IV ketorolac following ERCP.

    San Francisco, California and other locations

  • Internet Based Cognitive Behavioral Therapy in Pediatric Chronic Pancreatitis

    Sorry, not yet accepting patients

    Abdominal pain is common in children with chronic pancreatitis (CP), and as they continue into adulthood, the disease progresses with increased pain and greater exposure to opioids. Despite the relevancy of early pain self-management for childhood CP, there have been no studies of non-pharmacological pain intervention in this population. The proposed project will evaluate a web-based cognitive behavioral pain management program delivered to a cohort of well-phenotyped children with CP to reduce pain, pain-related disability and enhance HRQOL and will identify genetic risk factors and clinical and behavioral phenotypic factors associated with treatment response to enable precision medicine approaches.

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