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Pancreatitis clinical trials at UCSF

3 in progress, 1 open to eligible people

Pancreatitis is inflammation of the pancreas that causes belly pain and digestive problems. UCSF is collecting blood, saliva, urine, and stool from children with pancreatitis to identify gene mutations linked to higher pancreatic cancer risk. Samples are analyzed for DNA changes and stored for research on disease risk.

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  • Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

    open to eligible people ages up to 17 years

    This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic markers among pediatric patients with acute recurrent pancreatitis and chronic pancreatitis may help identify patients who are at risk of pancreatic cancer.

    Oakland, California and other locations

  • Indomethacin for Biliary ERCP Patients

    Sorry, not yet accepting patients

    This study is a randomized clinical trial evaluating the efficacy of rectal indomethacin in preventing post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in patients undergoing biliary ERCP who have a history of prior biliary sphincterotomy. While rectal indomethacin has demonstrated benefits in preventing post-ERCP pancreatitis in high-risk patients, its utility in this specific patient subgroup remains unclear. This trial aims to determine whether prophylactic administration of indomethacin offers a measurable benefit over no intervention in this lower-risk population. Eligible patients will be identified prior to their scheduled biliary ERCP and screened for inclusion criteria. Following informed consent, participants will be randomized to receive either rectal indomethacin or no indomethacin prior to the procedure.

    San Francisco, California

  • Study of TPIAT

    Sorry, in progress, not accepting new patients

    Multi-center, prospective, observational cohort study of patients undergoing total pancreatectomy with islet autotransplantation (TPIAT)

    San Francisco, California and other locations

Our lead scientists for Pancreatitis research studies include .

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