Substance Abuse clinical trials at UCSF
10 in progress, 7 open to eligible people
Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder
open to eligible people ages 18 years and up
VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in opioid treatment and in sustaining opioid abstinence…
San Francisco, California and other locations
Contingency Management for Veteran Smokers Undergoing Major Elective Surgery
open to eligible people ages 18 years and up
The goal of this study is to design and test the first mobile contingency management (CM) smoking cessation intervention for military Veterans undergoing major elective surgery. Smoking is the leading risk factor for postoperative complications and…
San Francisco, California
Cultural Adaptation of Drug Treatment for DJJ Youth
open to eligible people ages 12-17
This project aims to improve the understanding of the impact of Ethnic and Racial Discrimination (ERD) on adolescent alcohol and other drug use (AOD) within the Black Justice-Involved Youth (JIY) population. Individual interviews with Black JIY and…
San Francisco, California and other locations
Intervention for Virologic Suppression in Youth
open to eligible people ages 18-29
The goal of this randomized clinical trial is to test the effect of a technology-based intervention with an Adaptive Treatment Strategy (ATS) among youth living with HIV (YLWH) (18-29 years old). This piloted and protocolized intervention combines:…
San Francisco, California
Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.
open to eligible people ages 18-99
The purpose of this clinical trial is to compare the effectiveness of office-based methadone with pharmacy administration and/or dispensing to office-based buprenorphine for the treatment of opioid use disorder. This study will also examine factors…
San Francisco, California and other locations
Smoking Cessation CM for Veterans With or at Risk for Cancer
open to eligible people ages 18 years and up
Tobacco use among US Veterans poses significant health problems and challenges to their overall well-being. The aim of this project is to evaluate the effectiveness of a program called Contingency Management (CM) in helping Veterans quit smoking…
San Francisco, California
Technology to Reduce Youth Substance Use
open to eligible people ages 13-18
The research project will focus on conducting a trial of whether a tailored SMS text-messaging intervention is efficacious in improving justice-involved youths' substance use or dual diagnosis treatment attendance and engagement.
San Francisco, California
FostrSpace-CASA R61/R33
Sorry, in progress, not accepting new patients
The purpose of this study is to understand how an online digital health application (app) called FostrSpace can reduce substance use among youth (ages 13-20 years old) in foster care.
San Francisco, California
N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use
Sorry, in progress, not accepting new patients
Tobacco and cannabis co-use is a common and growing public health problem, especially in states that have legalized cannabis. There are no pharmacologic treatments for co-occurring tobacco and cannabis use. Co-use may make quitting either substance…
San Francisco, California
Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department
Sorry, not yet accepting patients
The overarching goal of this proposal is to integrate patient social risk information into an existing electronic health record (EHR)-based clinical decision support (CDS) tool (CDSv1) to facilitate emergency department (ED)-initiated, social…
San Francisco, California
Our lead scientists for Substance Abuse research studies include Andy Tompkins, MD Paula Lum, MD Parya Sabari, PharmD Melanie F Molina, MD, MAS Marina Tolou-Shams, PhD Ellen Herbst, MD.
Last updated: