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Septic Shock clinical trials at UCSF

1 research study open to eligible people

Septic shock is when a severe infection makes blood pressure fall and organs stop working properly. UCSF is testing hydrocortisone in children with septic shock in a randomized controlled study. UCSF is also collecting blood samples and studying medicines used to support blood pressure and immunity.

Showing trials for
  • Stress Hydrocortisone In Pediatric Septic Shock

    open to eligible people ages 1 month to 17 years

    SHIPSS is a multi-institutional, prospective, controlled, randomized, double-blinded interventional trial that will examine the potential benefits and risks of adjunctive hydrocortisone prescribed for children with fluid and vasoactive-inotropic refractory septic shock. It is hypothesized that adjunctive hydrocortisone will significantly reduce the incidence of new and progressive organ dysfunction (primary outcome) and proportion of children with poor outcomes, defined as death or severely impaired health-related quality of life (HRQL) (secondary outcome), as assessed at 28 days following study enrollment (randomization).

    Oakland, California and other locations

Our lead scientists for Septic Shock research studies include .