Obstetric Complication clinical trials at UCSF

2 in progress, 1 open to eligible people

Obstetric complications are health problems that occur during pregnancy. UCSF is studying if using CPAP machines can help pregnant people with sleep apnea. This trial involves 1,500 participants to see if this treatment improves health outcomes.

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  • Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

    open to eligible females ages 18 years and up

    A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate of hypertensive disorders of pregnancy.

    San Francisco, California and other locations

  • Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial

    Sorry, not currently recruiting here

    This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo. Both groups also will receive standard of care preoperative antibiotics (excluding azithromycin). The primary endpoint is a maternal infection composite defined as any one of the following up to 6 weeks postpartum: endometritis, wound infection, abscess, septic thrombosis, sepsis, pneumonia, pyelonephritis and breast infection.

    San Francisco, California and other locations

Our lead scientists for Obstetric Complication research studies include .

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