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End Stage Renal Disease clinical trials at UCSF

4 in progress, 3 open to eligible people

End stage renal disease is when the kidneys stop working completely. UCSF is studying the impact of genetics on kidney transplant outcomes and donor safety. They are testing a drug for severe kidney disease in patients with a rare condition. UCSF is also exploring ways to manage blood pressure in those receiving dialysis.

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  • DCR-PHXC in Patients With PH1 and ESRD

    open to all eligible people

    The aim of this study is to evaluate DCR-PHXC in participants with PH1 and severe renal impairment, with or without dialysis.

    San Francisco, California and other locations

  • Home Blood Pressure (BP) Trial

    open to eligible people ages 18 years and up

    The main study will be a two arm 10-month, cross-over randomized controlled trial of 200 participants treated with end-stage-kidney-disease treated with in-center hemodialysis in the Seattle and San Francisco area comparing a strategy of targeting…

    San Francisco, California and other locations

  • APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

    open to all eligible people

    The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a…

    San Francisco, California and other locations

  • Adding Urea to the Final Dialysis Fluid

    Sorry, not yet accepting patients

    At times patients with advanced renal failure present with severe hyperkalemia or acidosis and very high serum blood urea nitrogen (BUN) concentrations. These patients cannot be dialyzed aggressively as the lowering of serum BUN may results in…

    San Francisco, California

Our lead scientists for End Stage Renal Disease research studies include .

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