CAR T-Cell Therapy clinical trials at UCSF
2 research studies open to eligible people
CAR T-Cell Therapy is a cancer treatment that uses the patient's own immune cells to attack cancer cells. UCSF has clinical trials for CAR T-Cell Therapy. One trial is testing an improved version of the treatment for patients with multiple myeloma. Another trial is studying the long-term safety and effectiveness of the treatment. Patients who have previously received the treatment are eligible to participate.
CAR-T Long Term Follow Up (LTFU) Study
open to all eligible people
Per Health Authorities guidelines for gene therapy medicinal products that utilize integrating vectors (e.g. lentiviral vectors), long term safety and efficacy follow up of treated patients is required. The purpose of this study is to monitor all patients exposed to CAR-T therapied for 15 years following their last CAR-T (e.g. CTL019) infusion to assess the risk of delayed adverse events (AEs), monitor for replication competent lentivirus (RCL) and assess long-term efficacy, including vector persistence.
San Francisco, California and other locations
MM CAR-T to Upgrade Response BMTCTN1902
open to eligible people ages 18-71
This study is designed as a Phase II, multicenter, single arm trial to assess anti-B Cell Maturation Antigen (BCMA) chimeric antigen receptor (CAR) T-cells (bb2121) to improve post autologous hematopoietic cell transplant (HCT) responses among patients with multiple myeloma (MM).
San Francisco, California and other locations
Last updated: