Dermatomyositis clinical trials at UCSF
3 in progress, 1 open to eligible people
Dermatomyositis is a disorder that leads to muscle weakness and skin rashes. UCSF is exploring the effects of a treatment called efgartigimod on adults with this condition. The trial focuses on evaluating the safety and effectiveness of the treatment for muscle inflammation.
Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
open to eligible people ages 18 years and up
This study's purpose is to measure the treatment response from efgartigimod PH20 SC compared with placebo in participants with Idiopathic Inflammatory Myopathy (IIM). Participants with the IIM subtypes of dermatomyositis (DM), immune-mediated necrotizing myopathy (IMNM), or certain other subtypes of polymyositis (PM; including antisynthetase syndrome [ASyS]) will be included in the study. Treatment response will be measured by Total improvement score (TIS). Additional information can be found on https://myositis-study.com/.
San Francisco, California and other locations
Long-term Safety and Efficacy of a Subcutaneous Formulation of Efgartigimod in Adults With Active Idiopathic Inflammatory Myopathy
Sorry, accepting new patients by invitation only
The purpose of this study is to measure the long-term safety and tolerability of efgartigimod PH20 SC in adult participants with IIM who previously participated in ARGX-113-2007. Secondary objectives include efficacy measures of efgartigimod PH20 SC in participants with IIM.
San Francisco, California and other locations
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
Sorry, not currently recruiting here
RESET-Myositis: Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects with Active Idiopathic Inflammatory Myopathy or Juvenile Idiopathic Inflammatory Myopathy
San Francisco, California and other locations
Our lead scientists for Dermatomyositis research studies include Susan Kim, MD, MMSc.
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