Stress clinical trials at UCSF
11 in progress, 6 open to eligible people
Biological and Behavioral Outcomes of Community Nature Walks
open to eligible people ages 18 years and up
The investigators will test the efficacy of our proposed intervention to reduce embodied stress in four racial/ethnic groups (Black, Latinx, Pilipinx, and Pacific Islander) as a preventative intervention for health disparities found in these…
San Francisco, California
Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder
open to eligible people ages 18-75
This study will investigate treatments for insomnia in Veterans who have posttraumatic stress disorder (PTSD). The purpose of this study is to compare a brief behavioral treatment for insomnia (BBTI) to a treatment that helps promote relaxation…
San Francisco, California
Inflammatory Challenge and Fear
open to eligible people ages 25-45
The goal of this study is to learn if short-term changes in the immune system alter how we process information and experience fear. The main questions it aims to answer are: Do people who receive typhoid vaccine respond differently than those who…
San Francisco, California
Parenting Stress mHealth
open to eligible people ages 12 years and up
Parenting stress is a well-documented barrier to youth engagement in community-based substance use treatment. The current project aims to develop and evaluate a mobile health parenting stress intervention for caregivers of justice-involved youth, a…
San Francisco, California
Selective Glucocorticoid Receptor Antagonist in the Treatment of Veterans With Posttraumatic Stress Disorder (PTSD) (Seven Study)
open to eligible people ages 18-69
The purpose of this study is to test the drug CORT108297, which blocks the hormone cortisol, for treatment of PTSD in Veterans, and establish a safety profile that will inform the design of future studies.
San Francisco, California and other locations
Suvorexant: A Dual Orexin Receptor Antagonist for Treating Sleep Disturbance in Posttraumatic Stress
open to eligible people ages 18-75
Post-traumatic stress disorder (PTSD) is a common consequence of combat that can result in trauma-related hyperarousal and sleep disturbances. Poor sleep, one of the most common complaints in Veterans with PTSD, can be distressing, impair…
San Francisco, California and other locations
Doxazosin for Nightmares, Sleep Disturbance, and Non-Nightmare Clinical Symptoms in PTSD
Sorry, in progress, not accepting new patients
This randomized, double-blind, placebo-controlled trial of doxazosin will assess doxazosin's effectiveness for PTSD nightmares, subjective sleep quality, and non-nightmare PTSD symptoms in adult men and women veterans with full and partial-syndromal …
San Francisco, California
Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Sorry, not yet accepting patients
Sleep disturbance is a major problem in Veterans with posttraumatic stress disorder (PTSD). This study will test a version of a sleep treatment that's been shown to be effective in the general population, with some changes to tailor it to the needs…
San Francisco, California
Healthcare Worker Resilience as Measured by Physiologic Feedback
Sorry, in progress, not accepting new patients
Reliably achieving peak performance requires balancing the strain of the prior day with sufficient recovery to be ready for the next day. Surgery has a long standing tradition long hours of hard work often at the expense of adequate sleep. Decreased …
Stanford, California
Modification of Attention Bias Remotely After Trauma
Sorry, in progress, not accepting new patients
The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final control condition with …
San Francisco, California
SCULPT-Job Cohort Study
Sorry, in progress, not accepting new patients
This is an research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
San Francisco, California
Our lead scientists for Stress research studies include Thomas C. Neylan, MD Johanna B Folk, PhD Anne Richards, MD, MPH Joshua Woolley, MD, PhD Sabra S Inslicht, PhD Joaquin Anguera, PhD Shira Maguen, PhD.
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