for people ages 18-55 (full criteria)
at San Francisco, California
study started
completion around
Principal Investigator
by Joshua Woolley, MD, PhDJoaquin Anguera, PhD
Headshot of Joshua Woolley
Joshua Woolley
Headshot of Joaquin Anguera
Joaquin Anguera



The investigators will complete an entirely remote randomized controlled trial (RCT) comparing 14 sessions of attention bias modification (ABM), attention control training (ACT), placebo neutral attention training, and a final control condition with daily questions in 1,897 individuals with clinically significant Post-traumatic Stress Symptoms (PTSS) (defined as PCL-5 score ≥ 33). To assess effects of the training and control conditions, the investigators will administer tests of threat-related attention bias and variability, and self-report assessments of PTSS, depression, anxiety, and perceived stress at baseline, after one and two weeks of training, and at eight-week follow up. The investigators plan to screen and confirm interest from over 3,000 eligible participants over a period of 24 months to enroll and randomize 1,897 participants with the end goal of 1,232 completers (176 per condition).

Official Title

Optimizing Attention Bias Modification for Posttraumatic Stress Disorder: An Entirely Remote Study


Post Traumatic Stress Disorder, Attention bias, Traumatic Stress Disorders, Post-Traumatic Stress Disorders, SMART Mobile App - Attention Bias Modification, Attention Bias Modification - Word Stimuli, Attention Bias Modification - Face Stimuli


You can join if…

Open to people ages 18-55

  • Aged 18 to 55 years
  • Score at or above 33 on the PCL-5,
  • Able and willing to perform daily smartphone training for two weeks
  • Fluent English comprehension.
  • Owns Android or iPhone smartphone

You CAN'T join if...

  • Does not have Android or iPhone Operating System (iOS) smartphone running sufficient software (i.e. at least iOS 10.1), and is not willing to update
  • Active suicidality.


  • Zoe Zong accepting new patients
    San Francisco California 94143 United States

Lead Scientists at UCSF

  • Joshua Woolley, MD, PhD
    Dr. Josh Woolley is an Associate Professor in Residence in the Department of Psychiatry and Behavioral Sciences at the University of California, San Francisco (UCSF) as well as a staff psychiatrist in Mental Health at the San Francisco Veterans Affairs Medical Center (SFVAMC). He is Board Certified in Psychiatry by the American Board of Psychiatry and Neurology.
  • Joaquin Anguera, PhD
    The body of research I developed during my graduate and postdoctoral training focused on characterizing & augmenting aspects of cognitive control & skill acquisition using behavioral and neuroimaging technologies.


accepting new patients
Start Date
Completion Date
University of California, San Francisco
Study Type
Expecting 1897 study participants
Last Updated