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Nausea clinical trials at UCSF

1 research study open to eligible people

Nausea is when you feel like you might throw up. At UCSF, we're studying how Olanzapine can help control this in children undergoing intense chemotherapy. The trial is centered on nausea and vomiting that comes from treating cancer.

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  • RCT of Olanzapine for Control of CIV in Children Receiving Highly Emetogenic Chemotherapy

    open to eligible people ages 30 months to 18 years

    Chemotherapy-induced nausea and vomiting (CINV) are among the most bothersome symptoms during cancer treatment according to children and their parents. Most children receiving highly emetogenic chemotherapy (HEC), including those receiving hematopoietic stem cell transplant (HSCT) conditioning, experience CIV despite receiving antiemetic prophylaxis. Olanzapine improves CINV control in adult cancer patients, has a track record of safe use in children with psychiatric illness, does not interact with chemotherapy and is inexpensive. We hypothesize that the addition of olanzapine to standard antiemetics will improve chemotherapy-induced vomiting (CIV) control in children receiving highly emetogenic chemotherapy

    San Francisco, California and other locations

Our lead scientists for Nausea research studies include .

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