RAS Mutation clinical trials at UCSF

2 in progress, 1 open to eligible people

Showing trials for

  • ABM-168 in Adults With Advanced Solid Tumors.

    open to eligible people ages 18 years and up

    This is a Phase 1, First-in-Human (FIH), open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of ABM-168 in adult patients with RAS or RAF or NF-1 mutated advanced solid tumors as ABM-168 may have a significant effect in inhibiting cell growth.

    San Francisco, California and other locations

  • NAUTILUS: OKI-179 Plus Binimetinib in Patients With Advanced Solid Tumors in the RAS Pathway (Phase 1b) and NRAS-mutated Melanoma (Phase 2)

    Sorry, in progress, not accepting new patients

    The NAUTILUS study is a Phase 1b/2, multi-center, open-label study in which patients with activating mutations in the RAS pathway (Phase 1b) and patients with NRAS-mutated Melanoma (Phase 2) will be treated with a combination of oral OKI-179 combined with the MEK inhibitor binimetinib.

    San Francisco, California and other locations

Our lead scientists for RAS Mutation research studies include .

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