Anaplastic Ganglioglioma clinical trials at UCSF
1 research study open to eligible people
Anaplastic Ganglioglioma is a type of brain tumor. UCSF is conducting a clinical trial for patients with this tumor. The trial is testing a drug combination called dabrafenib and trametinib after radiation therapy to see how well it works.
Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma
open to eligible people ages 12 months to 21 years
This phase II trial studies how well the combination of dabrafenib and trametinib works after radiation therapy in children and young adults with high grade glioma who have a genetic change called BRAF V600 mutation. Radiation therapy uses high energy rays to kill tumor cells and reduce the size of tumors. Dabrafenib and trametinib may stop the growth of tumor cells by blocking BRAF and MEK, respectively, which are enzymes that tumor cells need for their growth. Giving dabrafenib with trametinib after radiation therapy may work better than treatments used in the past in patients with newly-diagnosed BRAF V600-mutant high-grade glioma.
San Francisco, California and other locations
Our lead scientists for Anaplastic Ganglioglioma research studies include Alyssa T. Reddy.