Antibiotic Prophylaxis clinical trials at UCSF

2 in progress, 0 open to eligible people

Showing trials for

  • Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial

    Sorry, in progress, not accepting new patients

    The Antibiotic Prophylaxis in Patients Undergoing Elective Total Knee Arthroplasty (TKA): Multi-Center Trial is a study that will compare the effectiveness of various perioperative strategies for antibiotic delivery as prophylaxis for periprosthetic joint infections (PJI) and surgical site infection in elective primary TKA. The investigators hypothesize that a single dose of prophylactic antibiotic administered within 60 minutes before the incision is not an effective way to prevent PJI in elective primary total knee arthroplasty (TKA). The investigators also hypothesize that the prolonged delivery (24 hours) of antibiotic prophylaxis after surgery does not further reduce the incidence of PJI in elective primary TKA. Duke University is the only site recruiting both primary total knee arthroplasty and unilateral knee arthroplasty.

    San Francisco, California and other locations

  • Antibiotics for Kidney Transplant Recipients

    Sorry, not yet accepting patients

    The goal of this clinical trial is to learn if a common antibiotic called trimethoprim-sulfamethoxazole (TMP-SMX) can help prevent urinary tract infections (UTIs) in children and young adults who recently had a kidney transplant. Most people take TMP-SMX for about 6 months after getting a kidney transplant. In this study, researchers want to see what happens if people keep taking it for 6 more months. The main questions this study is asking are: - Does TMP-SMX lower the number of UTIs in the first year after transplant? - What side effects or problems do participants have while taking TMP-SMX? Researchers will compare TMP-SMX to a placebo (a look-alike pill that does not contain any medication) to see if TMP-SMX works to prevent UTIs. Participants will: - Take either TMP-SMX or a placebo pill by mouth every day for 6 months - Have three visits to touch base with the study team about any issues - Complete short monthly online surveys about any symptoms or side effects - Share blood and urine test results from their regular transplant clinic visits

    San Francisco, California

Our lead scientists for Antibiotic Prophylaxis research studies include .

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