Calcium Release Deficiency Syndrome (CRDS) clinical trials at UCSF

1 research study open to eligible people

CRDS is a genetic disorder affecting the heart's ability to release calcium properly, which can lead to dangerous arrhythmias. UCSF is investigating new diagnostic tests to identify CRDS. One study examines how these tests can help detect the risk of sudden cardiac issues in patients.

Showing trials for

  • Clinical Diagnostic Test for CRDS

    open to all eligible people

    Calcium Release Deficiency Syndrome (CRDS) is a novel inherited arrhythmia syndrome secondary to RyR2 loss-of-function that confers a risk of sudden cardiac death. Diagnosis of CRDS presently requires cellular-based in vitro confirmation that an RyR2 variant causes loss-of-function. We hypothesize that CRDS can be diagnosed clinically through evaluation of the repolarization response to brief tachycardia, mediated by cardiac pacing, and a subsequent pause.

    San Francisco, California and other locations

Our lead scientists for Calcium Release Deficiency Syndrome (CRDS) research studies include .

Last updated: