Calcium Release Deficiency Syndrome (CRDS) clinical trials at UCSF
1 research study open to eligible people
Calcium release deficiency syndrome (CRDS) is a genetic disease of the heart that can lead to dangerous rhythms. UCSF is testing a clinical diagnostic tool to find CRDS by measuring RyR2 function. UCSF is collecting clinical data and biological samples for analysis.
Clinical Diagnostic Test for CRDS
open to all eligible people
Calcium Release Deficiency Syndrome (CRDS) is a novel inherited arrhythmia syndrome secondary to RyR2 loss-of-function that confers a risk of sudden cardiac death. Diagnosis of CRDS presently requires cellular-based in vitro confirmation that an RyR2 variant causes loss-of-function. We hypothesize that CRDS can be diagnosed clinically through evaluation of the repolarization response to brief tachycardia, mediated by cardiac pacing, and a subsequent pause.
San Francisco, California and other locations
Our lead scientists for Calcium Release Deficiency Syndrome (CRDS) research studies include Vasanth Vedantham.
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