CD20 Positive clinical trials at UCSF
1 research study open to eligible people
CD20 Positive refers to a protein found on some cancer cells. UCSF is recruiting patients for a clinical trial for mantle cell lymphoma. The trial studies the effects of rituximab with or without stem cell transplant in preventing the growth and spread of cancer cells in patients who are in their first complete remission.
Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission
open to eligible people ages 18-70
This randomized phase III trial studies rituximab after stem cell transplant and to see how well it works compared with rituximab alone in treating patients with in minimal residual disease-negative mantle cell lymphoma in first complete remission. Monoclonal antibodies, such as rituximab, may interfere with the ability of cancer cells to grow and spread. Giving chemotherapy before a stem cell transplant helps kill any cancer cells that are in the body and helps make room in the patient's bone marrow for new blood-forming cells (stem cells) to grow. After treatment, stem cells are collected from the patient's blood and stored. More chemotherapy is then given to prepare the bone marrow for the stem cell transplant. The stem cells are then returned to the patient to replace the blood-forming cells that were destroyed by the chemotherapy. Giving rituximab with or without stem cell transplant may work better in treating patients with mantle cell lymphoma.
San Francisco, California and other locations
Our lead scientists for CD20 Positive research studies include Lawrence D. Kaplan.